全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:... Ayyanar Sivanantham , Rajaguru Palanichamy , Subbiah Rajasekaran
来源:[J].Pharmacological Reports(IF 1.965), 2017, Vol.69 (3), pp.426-431Springer
摘要:Abstract(#br)Background(#br)Epithelial mesenchymal transition (EMT) is a process through which epithelial cells undergo multiple biochemical changes, causing them to differentiate into a mesenchymal-cell phenotype. This process has been shown to contribute to the development...
作者:... Rajaguru Palanichamy , Karthikeyan Muthusamy , Subbiah Rajasekaran
来源:[J].Inflammation Research(IF 1.964), 2019, Vol.68 (12), pp.1011-1024Springer
摘要:Abstract(#br) Background(#br)Polarized macrophages induce fibrosis through multiple mechanisms, including a process termed epithelial-to-mesenchymal transition (EMT). Mesenchymal cells contribute to the excessive accumulation of fibrous connective tissues, leading to organ failur...
作者:... Rajesh K. Thimmulappa , Vilwanathan Ravikumar , Subbiah Rajasekaran
来源:[J].Clinical Reviews in Allergy & Immunology(IF 5.59), 2018, Vol.54 (3), pp.480-492Springer
摘要:Abstract(#br)Lack of markers of subclinical disease state and clinical phenotype other than pulmonary function test has made the diagnosis and interventions of environmental respiratory diseases a major challenge. MicroRNAs (miRNAs), small non-coding single stranded RNAs, have em...
作者:Subbiah Rajasekaran , Vivia Yu-Ying Kao ...
来源:[J].Molecular Imaging and Biology(IF 3.095), 2010, Vol.12 (2), pp.163-173Springer
摘要:Abstract(#br) Purpose(#br)Among different chemokines, monocyte chemoattractant protein-1 (MCP-1) plays an important role in inflammatory disorders of lung. In response to stimuli, MCP-1 increases its transcription as an immediate early gene. In this paper, we describe the MC...
作者:Subbiah Rajasekaran , Narsa M Reddy ...
来源:[J].2013, Vol.14 (1), pp.381BMC
摘要:The Fra-1/AP-1 transcription factor regulates the expression of genes controlling various processes including migration, invasion, and survival as well as extracellular remodeling. We recently demonstrated that loss of Fra-1 leads to exacerbated bleomycin-induced pulmonary fibros...
作者:Subbiah Rajasekaran , Kasiappan Ravi ...
来源:[J].Clinical and Experimental Pharmacology and Physiology(IF 2.16), 2006, Vol.33 (3), pp.232-237Wiley
摘要:SUMMARY(#br) 1 The effect of diabetes mellitus on lipid metabolism is well established. The association of hyperglycaemia with an alteration of lipid parameters presents a major risk for cardiovascular complications in diabetes. Man...
作者:Subbiah Rajasekaran , Michelle Vaz , Sekhar P. Reddy
来源:[J].PLOS ONE(IF 3.73), 2012, Vol.7 (7)PLOS
摘要:The Fra-1/AP-1 transcription factor plays a key role in tumor epithelial cell progression; however, its role in pathogenic lung fibrosis remains unclear. In the present study, using a genetic approach (Fra-1 deficient mice), we have demonstrated a novel regulatory (protectiv...
作者:Subbiah Rajasekaran , Chandramohan R. Tamatam ...
来源:[J].AJP: Lung Cellular and Molecular Physiology(IF 3.523), 2015, Vol.309 (4), pp.L414-L424Duke University Press
摘要:Inappropriate lung inflammatory response following oxidant and toxicant exposure can lead to abnormal repair and disease pathogenesis, including fibrosis. Thus early detection of molecular and cellular processes and mediators promoting lung inflammation is necessary to develop be...

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