全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Heloise Brice , Jonathan Clayden , Stuart D. Hamilton
来源:[J].Beilstein Journal of Organic Chemistry(IF 2.801), 2010, Vol.6 (1), pp.22DOAJ
摘要:The silyl enol ether derivatives of ketones or esters tethered by a hydrocarbon or ether linkage to the 3-position of a pyridine ring undergo dearomatising nucleophilic attack on the ring once it is activated (as an acylpyridinium species) by the addition of methyl chloroformate....
作者:Heloise Brice , Jonathan Clayden , Stuart D. Hamilton
来源:[J].Beilstein Journal of Organic Chemistry(IF 2.801), 2010, Vol.6 (1)DOAJ
摘要:The silyl enol ether derivatives of ketones or esters tethered by a hydrocarbon or ether linkage to the 3-position of a pyridine ring undergo dearomatising nucleophilic attack on the ring once it is activated (as an acylpyridinium species) by the addition of methyl chloroformate....
作者:Jonathan Clayden , Stuart D. Hamilton , Rukhsana T. Mohammed
来源:[J].Organic Letters(IF 6.142), 2005, Vol.7 (17), pp.3673-3676ACS
摘要:Lithiation of N-benzyl pyridine and quinoline carboxamides α to nitrogen gives anions that undergo intramolecular attack on the pyridine or quinoline ring, either directly or on activation of the ring by N-acylation. The resulting four-, five-, or six-...
作者:Gareth Arnott , Jonathan Clayden , Stuart D. Hamilton
来源:[J].Organic Letters(IF 6.142), 2006, Vol.8 (23), pp.5325-5328ACS
摘要:β-Lactam cyclization product 3c was obtained in excellent yield, but in contrast with 2a and 2c the cyclizations of less hindered isonicotinamides 2b, 2d, and 2e were accompanied by competing Claisen acylation yielding 11 (tentatively identified in the crude reaction product...

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