全部文献期刊会议图书|学者科研项目
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作者:Stoyan Chakarov , Albena Momchilova
来源:[J].Materials Science & Engineering C(IF 2.404), 2017, Vol.78, pp.230-238
摘要:Abstract(#br)The present study describes a live-cell biosensor, suitable for general evaluation of adhesion qualities of different substrates. It is based on NIH/3T3 fibroblast cell line stably expressing fusion fluorescently tagged proteins mCherry-vinculin and GFP-tensin as qua...
作者:... Sashka Zhelyazkova , Ivaylo Tournev , Stoyan Chakarov
来源:[J].Biotechnology & Biotechnological Equipment(IF 0.622), 2018, Vol.32 (6), pp.1558-1566
摘要:Abstract(#br)Efficient maintenance of the integrity of the endothelium of cerebral blood vessels is crucially important, especially when the vessel walls are subjected to greater-than-normal levels of stress. Persistently high levels of genotoxic stress may result from lower...
作者:... Nikolai Zhelev , Roumen Pankov , Stoyan Chakarov
来源:[J].Biotechnology & Biotechnological Equipment(IF 0.622), 2018, Vol.32 (6), pp.1352-1358
摘要:Abstract(#br)Public and private human stem cell banking institutions are currently hosting hundreds of thousands partially characterized cell populations, including a significant number of human pluripotent stem cell lines. To be considered for use in clinical applications, stem ...
作者:... Rumena Petkova , Stoyan Chakarov , Tatyana Vlaykova
来源:[J].Biotechnology & Biotechnological Equipment(IF 0.622), 2015, Vol.29 (2), pp.351-356
摘要:Matrix metalloproteinases (MMPs) are a family of highly homologous extracellular Zn2+-dependent endopeptidases, also known as matrixins. MMP-2 (gelatinase A) and MMP-9 (gelatinase B) are considered to play a key role in a variety of physiological processes as well...
作者:... Pavlina Chelenkova , Ivaylo Tournev , Stoyan Chakarov
来源:[J].Biotechnology & Biotechnological Equipment(IF 0.622), 2016, Vol.30 (4), pp.623-643
摘要:ABSTRACT(#br)Neurons in the adult central nervous system (CNS) are subjected to high levels of oxidative damage that is usually promptly repaired. Transcribed genomic regions are repaired with priority over untranscribed regions. The prioritization of DNA repair in neurons result...
作者:Rumena Petkova , Stoyan Chakarov
来源:[J].Biotechnology & Biotechnological Equipment(IF 0.622), 2016, Vol.30 (3), pp.434-442
摘要:ABSTRACT(#br)The mechanisms for identification of DNA damage and repair usually manage DNA damage very efficiently. If damaged cells manage to bypass the checkpoints where the integrity of the genome is assessed and the decisions whether to proceed with the cell cycle are made, t...
作者:Stoyan Chakarov , Rumena Petkova , George Ch. Russev
来源:[J].Biotechnology & Biotechnological Equipment(IF 0.622), 2012, Vol.26 (1), pp.2695-2702
摘要:ABSTRACT(#br)p53 is a master regulator of the cell cycle, capable of assessing the severity and the scope of damage to the cellular DNA, integrating the signals from the cell under stress and delivering the final decision about the destiny of the cell—undertaking repair acti...
作者:Stoyan Chakarov , Ivana Roeva , George Russev
来源:[J].Biotechnology & Biotechnological Equipment(IF 0.622), 2011, Vol.25 (3), pp.2505-2507
摘要:ABSTRACT(#br)Cellular DNA is constantly subjected to a significant amount of damage resulting from extracellular as well as intracellular processes. There are various mechanisms to repair DNA damage among which nucleotide excision repair (NER) pathway has the highest degree of ve...

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