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作者:... Dan Buzatu , Stephen Harris , Jon Wilkes
来源:[J].BMC Bioinformatics(IF 3.024), 2017, Vol.18 (14)Springer
摘要:Blockage of some ion channels and in particular, the hERG (human Ether-a’-go-go-Related Gene) cardiac potassium channel delays cardiac repolarization and can induce arrhythmia. In some cases it leads to a potentially life-threatening arrhythmia known as Torsade de Pointes (T...
作者:Stephen Harris , Shraddha Thakkar ...
来源:[J].BMC Bioinformatics(IF 3.024), 2019, Vol.20 (S2), pp.129-139DOAJ
摘要:Adverse Drug Reactions (ADRs) are of great public health concern. FDA-approved drug labeling summarizes ADRs of a drug product mainly in three sections, i.e., Boxed Warning (BW), Warnings and Precautions (WP), and Adverse Reactions (AR), where the severity of ADRs are intended to...

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