全部文献期刊会议图书|学者科研项目
中外文文献  中文文献  外文文献
作者:... Alessandra Falleni , Stefano Ruggieri , Antonio Paparelli
来源:[J].Brain Research(IF 2.879), 2006, Vol.1129, pp.174-190
摘要:Abstract(#br)The PC12 cell line is commonly used as a tool to understand the biochemical mechanisms underlying the physiology and degeneration of central dopamine neurons. Despite the broad use of this cell line, there are a number of points differing between PC12 cells and dopam...
作者:... Serena Batini , Stefano Ruggieri , Antonio Paparelli
来源:[J].Brain Research Bulletin(IF 2.935), 2004, Vol.65 (4), pp.275-290
摘要:Abstract(#br)This brief paper analyzes a few degenerative diseases expressing as movement disorders and featuring at sub-cellular level the presence of neuronal inclusions in selective brain regions. We will first draw a short draft of representative neurological diseases featuri...
作者:Stefano Ruggieri , Antonio Paparelli
来源:[J].Parkinsonism and Related Disorders(IF 3.274), 2008, Vol.14, pp.S180-S184
摘要:Abstract(#br)The major component of Lewy bodies in Parkinson's disease (PD) is α-synuclein, which is considered as a substrate of the ubiquitin–proteasome (UP) system, although autophagy seems to be equally involved. Here we discuss the co-existence of α-synuclein and protei...
作者:Stefano Ruggieri , Renato Tonielli ...
来源:[J].Geomorphology(IF 2.552), 2009, Vol.115 (1), pp.129-140
摘要:Abstract(#br)We present a high resolution DTM of the Palinuro Seamount (PS, Tyrrhenian Sea, Italy) resulting from the processing of multibeam swath bathymetry records acquired during the second leg of the “Aeolian 2007” cruise. PS consists of several superimposed volcanoes a...
作者:... Mario Sprovieri , Stefano Ruggieri , Ennio Marsella
来源:[J].Quaternary International(IF 1.962), 2010, Vol.232 (1), pp.228-237
摘要:Abstract(#br)A high-resolution morphological and geological inspection was carried out on the Palinuro Bank (39° 30′N, 14° 48′E), a volcanic complex made by several, coalescent volcanic features located on the Campanian continental slope (Eastern Tyrrhenian Sea, Italy)....
作者:... Ferdinando Nicoletti , Stefano Ruggieri , Francesco Fornai
来源:[J].Experimental Neurology(IF 4.645), 2006, Vol.201 (1), pp.24-31
摘要:Abstract(#br)Amphetamine derivatives are the most commonly abused drugs. These compounds have been known for many years to induce neurotoxicity. However, recent findings have highlighted novel alterations produced by amphetamines in the central nervous system consisting of n...
作者:Stefano Ruggieri , Antonio Paparelli
来源:[J].Brain Research(IF 2.879), 2010, Vol.1355, pp.195-206
摘要:Abstract(#br)Gastrointestinal (GI) dysfunction occurs frequently in early Parkinson's disease (PD) and it is supposed to anticipate motor symptoms. About 80% of PD patients suffer from constipation before the onset of movement disorders. Despite such a high prevalence of gut...
作者:... Francesco Orzi , Ferdinando Nicoletti , Stefano Ruggieri
来源:[J].Brain Research(IF 2.879), 2000, Vol.887 (1), pp.110-117
摘要:Abstract(#br)Despite a long-lasting therapeutic use of l -DOPA in Parkinson’s disease, doubts still remain concerning the possibility that chronic l -DOPA might accelerate the progression of this movement disorder. To address this point, in the present study we examined the ...
作者:Stefano Ruggieri , Luigi Murri ...
来源:[J].Parkinsonism and Related Disorders(IF 3.274), 2009, Vol.15, pp.S24-S27
摘要:Abstract(#br)In eukaryotic cells intracellular components are mainly degraded by autophagy and the ubiquitin-proteasome system. Autophagy is more flexible compared with the ubiquitin-proteasome system and it is involved in the degradation of long-lived proteins and organelles, su...
作者:... Francesco Orzi , Ferdinando Nicoletti , Stefano Ruggieri
来源:[J].Brain Research(IF 2.879), 2001, Vol.898 (1), pp.27-35
摘要:Abstract(#br)( R )-Apomorphine is a non-selective dopamine (DA) agonist which is used in the treatment of Parkinson’s disease. In addition to symptomatic effects, apomorphine exerts a neuroprotective activity in specific experimental models. For instance, apomorphine prevent...

我们正在为您处理中,这可能需要一些时间,请稍等。

资源合作:cnki.scholar@cnki.net, +86-10-82896619   意见反馈:scholar@cnki.net

×