全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
中外文文献  中文文献  外文文献
作者:Stefanie C. Fleck , Mona I. Churchwell , Daniel R. Doerge
来源:[J].Food and Chemical Toxicology(IF 3.01), 2017, Vol.106, pp.193-201Elsevier
摘要:Abstract(#br)Zearalenone (ZEN) is a well-studied mycotoxin whose potent estrogenic properties have been used by international regulatory bodies to set health-based guidance values for ZEN exposure in grain-based foods from changes in hormonally responsive tissues of juvenile...
作者:Stefanie C. Fleck , Nathan C. Twaddle ...
来源:[J].Food and Chemical Toxicology(IF 3.01), 2018, Vol.115, pp.511-522Elsevier
摘要:Abstract(#br)Biomonitoring of human exposure to estrogens most frequently focuses on environmental and dietary estrogens, and infrequently includes measures of exposure to potent endogenous estrogens present in serum. Pregnancy is a developmentally sensitive period during wh...
作者:Stefanie C. Fleck , Nathan C. Twaddle ...
来源:[J].Food and Chemical Toxicology(IF 3.01), 2018Elsevier
摘要:Abstract(#br)Evaluating the biological significance of human-relevant exposures to environmental estrogens involves assessing the individual and total estrogenicity of endogenous and exogenous estrogens found in serum, for example from biomonitoring studies. We developed a m...
作者:Stefanie C. Fleck , Dominique Thomas ...
来源:[J].Neuropharmacology(IF 4.114), 2019, Vol.146, pp.198-211Elsevier
摘要:Abstract(#br)Inhibitor-kappaB kinase epsilon (IKKε, Ikbke) constitutes an NF-κB activating kinase with high homology to the classical I-κB kinase subunits, IKKα and IKKβ. It is expressed in nociceptive neurons in the spinal cord and in dorsal root ganglia (DRG) and invo...
作者:Stefanie C. Fleck , Mona I. Churchwell ...
来源:[J].Food and Chemical Toxicology(IF 3.01), 2016, Vol.95, pp.19-27Elsevier
摘要:Abstract(#br)Urine and serum biomonitoring was used to measure internal exposure to selected dietary estrogens in a cohort of 30 pregnant women. Exposure was measured over a period comprising one-half day in the field (6 h) and one day in a clinic (24 h). Biomonitoring of th...
作者:Stefanie C. Fleck , Friederike Sauter ...
来源:[J].Mutation Research - Genetic Toxicology and Environmental Mutagenesis(IF 2.22), 2016, Vol.798-799, pp.27-34Elsevier
摘要:Abstract(#br)The Alternaria mycotoxins alternariol (AOH) and altertoxin II (ATX II) have previously been shown to elicit mutagenic and genotoxic effects in bacterial and mammalian cells, although with vastly different activities. For example, ATX II was about 50 times more m...
作者:... Mona I. Churchwell , Stefanie C. Fleck , William G. Helferich
来源:[J].Food and Chemical Toxicology(IF 3.01), 2016, Vol.92, pp.165-176Elsevier
摘要:Abstract(#br)Consumption of soy infant formula represents a unique exposure scenario in which developing children ingest a mixture of endocrine-active isoflavones along with a substantial portion of daily nutrition. Genistein and daidzein were administered as glucoside conjugates...
作者:Stefanie C. Fleck , Andreas A. Hildebrand ...
来源:[J].Toxicology Letters(IF 3.145), 2012, Vol.210 (1), pp.9-14Elsevier
摘要:Abstract(#br)α-Zearalanol (α-ZAL, zeranol) is a highly estrogenic macrocyclic β-resorcylic acid lactone, which is used as a growth promotor for cattle in various countries. We have recently reported that α-ZAL and its major metabolite zearalanone (ZAN) are hydroxylated at th...
作者:Stefanie C. Fleck , Britta Burkhardt ...
来源:[J].Toxicology Letters(IF 3.145), 2012, Vol.214 (1), pp.27-32Elsevier
摘要:Abstract(#br)Altertoxin II (ATX II) is one of the several mycotoxins produced by Alternaria fungi. It has a perylene quinone structure and is highly mutagenic in Ames Salmonella typhimurium , but its mutagenicity in mammalian cells has not been studied before. Here we report that...
作者:Stefanie C. Fleck , Daniel R. Doerge
来源:[J].Molecular Nutrition & Food Research(IF 4.31), 2015, Vol.59 (8), pp.1419-1430Wiley
摘要:Scope(#br)Soy flour diet (MS) prevented isoflavones from stimulating MCF‐7 tumor growth in athymic nude mice, indicating that other bioactive compounds in soy can negate the estrogenic properties of isoflavones. The underlying signal transduction pathways to explain the prot...

我们正在为您处理中,这可能需要一些时间,请稍等。

资源合作:cnki.scholar@cnki.net, +86-10-82896619   意见反馈:scholar@cnki.net

×