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作者:... Guido Sauter , Stefan Steurer , Eike Burandt
来源:[J].Gynecologic Oncology(IF 3.929), 2020, Vol.156 (3), pp.669-675
摘要:Abstract(#br)Objective(#br)Mismatch repair (MMR) deficiency and Bethesda panel microsatellite instability (MSI) are increasingly analyzed to identify tumors that might benefit from immune checkpoint inhibitors, but tumor heterogeneity is a potential obstacle for such analyses. In...
作者:Stefan Steurer , Claudia Hube-Magg ...
来源:[J].Molecular Medicine(IF 4.469), 2020, Vol.26 (1), pp.1252-1259
摘要:Abstract(#br)Background(#br)TFAP2D is a transcription factor important for modulating gene expression in embryogenesis. Its expression and prognostic role in prostate cancer has not been evaluated. Methods(#br)Therefore, a tissue microarray containing 17,747 prostate cancer ...
作者:Stefan Steurer , Michael Rink ...
来源:[J].Human Pathology(IF 2.843), 2017, Vol.61, pp.210-220
摘要:Summary(#br)Development of genetic instability is a hallmark of tumor progression. Type III β -tubulin (TUBB3) is a component of microtubules involved in chromosome segregation. Its overexpression has been linked to adverse features of urinary bladder cancer. To investigate ...
作者:Stefan Steurer , Doris Höflmayer ...
来源:[J].Neoplasia, 2019, Vol.21 (9), pp.872-881
摘要:Abstract(#br)Dysregulation of S100A8 is described in many different human tumor types, but its role in prostate cancer is unknown. To evaluate the clinical relevance of S100A8 expression in prostate cancer, a tissue microarray containing 13,665 tumors was analyzed by immunohistoc...
作者:... Waldemar Wilczak , Guido Sauter , Stefan Steurer
来源:[J].Urologic Oncology: Seminars and Original Investigations(IF 3.647), 2019
摘要:Abstract(#br)Background(#br)Microsatellite instability (MSI), a hypermutator phenotype described in many cancers, has emerged as a predictive biomarker for immune checkpoint inhibitor therapy. Cancer heterogeneity represents a potential obstacle for the analysis of prediciti...
作者:Stefan Steurer , Corinna Wittmer ...
来源:[J].Neoplasia, 2017, Vol.19 (4), pp.279-287
摘要:Abstract(#br)The A Disintegrin and Metalloproteinase (ADAM) family of endopeptidases plays a role in many solid cancers and includes promising targets for anticancer therapies. Deregulation of ADAM15 has been linked to tumor aggressiveness and cell line studies suggest that ADAM1...
作者:Stefan Steurer , Guido Sauter ...
来源:[J].Disease Markers(IF 2.14), 2019, Vol.2019
摘要:Small-cell cancer of the urinary bladder is a rare but highly aggressive disease. It is currently unclear whether immune checkpoint therapies that have been approved for urothelial carcinomas will also be efficient in small-cell carcinomas. In this study, we analyzed potenti...
作者:Stefan Steurer , Corinna Wittmer ...
来源:[J].Neoplasia: An International Journal for Oncology Research, 2017, Vol.19 (4), pp.279-287
摘要:The A Disintegrin and Metalloproteinase (ADAM) family of endopeptidases plays a role in many solid cancers and includes promising targets for anticancer therapies. Deregulation of ADAM15 has been linked to tumor aggressiveness and cell line studies suggest that ADAM15 overexpress...
作者:Stefan Steurer , Meike Adam ...
来源:[J].Human Pathology(IF 2.843), 2015, Vol.46 (4), pp.514-523
摘要:Summary(#br)The cytosolic factor Saccharomyces cerevisiae –like 1 (SEC14L1) is a regulator of lipid metabolism and signaling pathways that has been suggested to play a role in cancer. To learn more about its relevance for prostate cancer, SEC14L1 expression was analyzed on a...
作者:Stefan Steurer , Guido Sauter ...
来源:[J].Experimental and Molecular Pathology(IF 2.128), 2015, Vol.98 (3), pp.419-426
摘要:Abstract(#br)Histone deacetylases (HDACs) play an important role in tumor development and progression by modifying histone and non-histone proteins. In the current study we analyzed prevalence and prognostic impact of HDAC1 in prostate cancer. HDAC1 expression was analyzed by imm...

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