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作者:Sohan S. Chitlange , Amir I. Mulla ...
来源:[J].Preparative Biochemistry and Biotechnology(IF 0.406), 2010, Vol.40 (4), pp.337-346
摘要:A stability-indicating thin layer chromatographic (TLC) method for determination of dexrabeprazole (DEX) and domperidone (DOM) in combined dosage form has been developed and validated. The mobile phase selected was acetone:toluene:methanol (4.5:4.5:0.5, v/v/v) with ultraviol...
作者:Sohan S. Chitlange , Rabindra K. Nanda
来源:[J].Anti-Cancer Agents in Medicinal Chemistry(IF 2.61), 2019, Vol.19 (9), pp.1080-1102
摘要:Background & Objective: Nitrogen mustard derivatives form one of the major classes of anti-canceragents in USFDA approved drugs list. These are polyfunctional alkylating agents which are distinguished by aunique mechanism of adduct formation with DNA involving cross-linking betwe...
作者:Amit S. Tapkir , Sohan S. Chitlange , Ritesh P. Bhole
来源:[J].Data in Brief, 2017, Vol.14, pp.469-473
摘要:Abstract(#br)Fragment based Quantitative structure activity relationship (QSAR) analysis on reported 25 2-(2-(4-aryloxybenzylidene) hydrazinyl) benzothiazole dataset as antitubercular agents were carried out. Molecules in the current dataset were fragmented into six fragments (R1...
作者:... K. Venkateswara Swamy , Rabindra K. Nanda , Sohan S. Chitlange
来源:[J].Data in Brief, 2019, Vol.25
摘要:Abstract(#br)Major Phytoconstituents of Actinidia deliciosa were explored for their anti-viral potential against dengue virus (DENV). The docking of these phytoconstituents was performed on 7 viral targets- 4 DENV non structural protein (NS5-SAM binding domain, NS5 RdRp doma...
作者:... Venkateswara K. Swamy , Rabindra K. Nanda , Sohan S. Chitlange
来源:[J].Data in Brief, 2019, Vol.24
摘要:Abstract(#br)Molecular docking analysis of twenty two phytoconstituents from Hibiscus rosa-sinensis , against seven targets of obesity like pancreatic lipase, fat and obesity protein (FTO protein), cannabinoid receptor, hormones as ghrelin, leptin and protein as SCH1 and MCH1 is ...
作者:Amit S. Tapkir , Sohan S. Chitlange , Ritesh P. Bhole
来源:[J].Data in Brief, 2017, Vol.14 (C), pp.469-473
摘要:Fragment based Quantitative structure activity relationship (QSAR) analysis on reported 25 2-(2-(4-aryloxybenzylidene) hydrazinyl) benzothiazole dataset as antitubercular agents were carried out. Molecules in the current dataset were fragmented into six fragments (R1, R2, R3, R4,...
作者:Amit S. Tapkir , Sohan S. Chitlange , Ritesh P. Bhole
来源:[J].Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry, 2017, Vol.16 (3), pp.175-192
摘要:Background: We have developed a new series of 36 substituted thiazole derivativesprepared via reaction of substituted benzothiazole-2-amine with substituted phenacylbromide. Objective: This study was aimed to develop and successfully evaluate anti-inflammatory activityof substitu...

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