全部文献期刊会议图书|学者科研项目
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作者:Simone Degan , Detlev Erdmann ...
来源:[J].Journal of Investigative Dermatology(IF 6.193), 2017, Vol.137 (2), pp.475-483Elsevier
摘要:Loss of function of KIND1, a cytoskeletal protein involved in β1-integrin function, causes Kindler syndrome, a genetic disease characterized by skin fragility, photosensitivity, and increased risk of squamous cell carcinoma. Dysregulation of β1-integrin underlies Kindler syn...
作者:Simone Degan , Bastiaan Driehuys
来源:[J].Journal of Magnetic Resonance(IF 2.3), 2018Elsevier
摘要:Abstract(#br)Hyperpolarized (HP) 129 Xe MRI is emerging as a powerful, non-invasive method to image lung function and is beginning to find clinical application across a range of conditions. As clinical implementation progresses, it becomes important to translate back to well-defi...
作者:Simone Degan , Detlev Erdmann ...
来源:[J].Journal of Investigative Dermatology(IF 6.193), 2016Elsevier
摘要:Loss of function of KIND1, a cytoskeletal protein involved in β1-integrin function, causes Kindler syndrome, a genetic disease characterized by skin fragility, photosensitivity, and increased risk of squamous cell carcinoma. Dysregulation of β1-integrin underlies Kindler syn...
作者:Simone Degan , Russell P. Hall ...
来源:[J].JOM(IF 0.986), 2016, Vol.68 (4), pp.1128-1133Springer
摘要:Abstract(#br)Itraconazole is a triazole agent that is routinely used for treatment of nail infections and other fungal infections. Recent studies indicate that itraconazole can also inhibit the growth of basal cell carcinoma (BCC) through suppression of the Sonic Hedgehog (S...
作者:Simone Degan , Michael Antonacci
来源:[J].Magnetic Resonance in Medicine(IF 3.267), 2017, Vol.78 (3), pp.1070-1079Wiley
摘要:Purpose(#br)To investigate the temperature dependence of the resonance frequency of lipid‐dissolved xenon (LDX) and to assess the accuracy of LDX‐based MR thermometry.(#br)Methods(#br)The chemical shift temperature dependence of water protons, methylene protons, and LDX was ...
作者:Simone Degan , Geoffry M. Schrank ...
来源:[J].Magnetic Resonance in Medicine(IF 3.267), 2017, Vol.77 (4), pp.1438-1445Wiley
摘要:Purpose(#br)129Xe interacts with biological media to exhibit chemical shifts exceeding 200 ppm that report on physiology and pathology. Extracting this functional information requires shifts to be measured precisely. Historically, shifts have been reported relativ...
作者:Simone Degan , Maura Leonard ...
来源:[J].The Journal of Allergy and Clinical Immunology(IF 12.047), 2011Elsevier
摘要:Background(#br)The characteristics of human asthma are chronic inflammation and airway remodeling. Hyaluronan, a major extracellular matrix component, accumulates during inflammatory lung diseases, including asthma. Hyaluronan fragments stimulate macrophages to produce infla...
作者:Simone Degan , Barbara S Theriot ...
来源:[J].British Journal of Pharmacology(IF 5.067), 2012, Vol.165 (7), pp.2365-2377Wiley
摘要:BACKGROUND AND PURPOSE Inhalation of a β‐adrenoceptor agonist (β‐agonist) is first‐line asthma therapy, used for both prophylaxis against, and acute relief of, bronchoconstriction. However, repeated clinical use of β‐agonists leads to impaired bronchoprotection and...

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