全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:... Kerstin Borgmann , Kathryn D. Held , Simon N. Powell
来源:[J].Journal of Biomedicine and Biotechnology(IF 2.88), 2008, Vol.2008DOAJ
摘要:Genetic or epigenetic inactivation of the pathway formed by the Fanconi anemia (FA) and BRCA1 proteins occurs in several cancer types, making the affected tumors potentially hypersensitive to DNA cross-linkers and other chemotherapeutic agents. It has been proposed that the ...
作者:Henning Willers , Fen Xia , Simon N. Powell
来源:[J].Journal of Biomedicine and Biotechnology(IF 2.88), 2002, Vol.2 (2), pp.86-93DOAJ
摘要:A major goal of current cancer research is to understand thefunctional consequences of mutations in recombinational DNArepair genes. The introduction of artificial recombinationsubstrates into living cells has evolved into a powerful tool toperform functional analysis of DNA doub...
作者:... Kerstin Borgmann , Kathryn D. Held , Simon N. Powell
来源:[J].Journal of Biomedicine and Biotechnology(IF 2.88), 2008, Vol.2008DOAJ
摘要:Genetic or epigenetic inactivation of the pathway formed by the Fanconi anemia (FA) and BRCA1 proteins occurs in several cancer types, making the affected tumors potentially hypersensitive to DNA cross-linkers and other chemotherapeutic agents. It has been proposed that the ...
作者:... Alphonse G. Taghian , Simon N. Powell , Ariel E. Hirsch
来源:[J].Clinical Breast Cancer(IF 2.422), 2013, Vol.13 (5), pp.344-349Elsevier
摘要:Abstract(#br)Background(#br)Male breast cancer (MBC) accounts for approximately 1% of all breast cancers. Given the rarity of this disease, treatment of MBC generally follows the same principles as treatment of female breast cancer. However, the traditional surgical approach...
作者:... Beryl McCormick , Simon N. Powell , Alice Y. Ho
来源:[J].Breast Cancer Research and Treatment(IF 4.469), 2013, Vol.139 (2), pp.497-506Springer
摘要:Abstract(#br)Triple-negative breast cancer (TNBC) disproportionately affects black women. However, black race as a prognostic factor in TNBC has not been well studied. We evaluated the effect of race, among other variables, on outcomes in women with TNBC. A total of 704 pati...
作者:Simon N. Powell , Zvi Fuks
来源:[J].Radiotherapy and Oncology(IF 4.52), 2014, Vol.111 (1), pp.88-93Elsevier
摘要:Abstract(#br)Background and purpose(#br)Single Dose Radiation Therapy (SDRT) provides remarkably high rates of control even for tumors resistant to fractionated radiotherapy. SDRT tumor control depends on acute acid sphingomyelinase-mediated endothelial cell injury and monoclonal...

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