全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:... Xiru Wu , Yan Chen , Shujie Yu
来源:[J].BMC Medical Genetics(IF 2.536), 2017, Vol.18 (1)Springer
摘要:SCN8A mutations have recently been associated with epilepsy and neurodevelopmental disorders. This study aimed to broaden the phenotypic-spectrum of disease related with SCN8A mutations.
作者:Shujie Yu , Hua Zhang
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.9 (5)DOAJ
摘要:The 26S proteasome plays a fundamental role in almost all eukaryotic cells, including vascular endothelial cells. However, it remains largely unknown how proteasome functionality is regulated in the vasculature. Endothelial nitric oxide (NO) synthase (eNOS)-derived NO is known to...
作者:Shujie Yu , Hua Zhang
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.7 (10)DOAJ
摘要:Diabetes impairs physiological angiogenesis by molecular mechanisms that are not fully understood. Methylglyoxal (MGO), a metabolite of glycolysis, is increased in patients with diabetes. This study defined the role of MGO in angiogenesis impairment and tested the mechanism in di...
作者:Shujie Yu , Hui Zhang ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.9 (11)DOAJ
摘要:We have previously reported that Ginsenoside Rb1 may effectively prevent HUVECs from senescence, however, the detailed mechanism has not demonstrated up to now. Recent studies have shown that sirtuin-1 (Sirt1) plays an important role in the development of endothelial senesce...

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