全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Shinya Kasai , Miho Tanaka ...
来源:[J].Molecular Brain(IF 4.202), 2017, Vol.10 (1)Springer
摘要:Dopamine is important for motor control and involved in the regulation of circadian rhythm. We previously found that dopamine-deficient (DD) mice became hyperactive in a novel environment 72 h after the last injection of L-3,4-dihydroxyphenylalanine (L-DOPA) when dopamine wa...
作者:Shinya Kasai , Kaori Yoshida ...
来源:[J].Journal of Pharmacological Sciences(IF 2.15), 2015, Vol.127 (3), pp.391-393Elsevier
摘要:Abstract(#br)An association between postoperative analgesic requirements in subjects who underwent orthognathic surgery and the rs1465040 single-nucleotide polymorphism close to the transient receptor potential subfamily C member 3 ( TRPC3 ) gene was suggested by our previous gen...
作者:Shinya Kasai , Junko Hasegawa ...
来源:[J].Molecular Brain(IF 4.202), 2015, Vol.8 (1)Springer
摘要:Abstract(#br) Background(#br)Many genetic and environmental factors are involved in the etiology of nicotine dependence. Although several candidate gene variations have been reported by candidate gene studies or genome-wide association studies (GWASs) to be associated with s...
作者:Shinya Kasai , Yasukazu Ogai ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.4 (9)DOAJ
摘要:Opioids are commonly used as effective analgesics for the treatment of acute and chronic pain. However, considerable individual differences have been widely observed in sensitivity to opioid analgesics. We focused on a G-protein-activated inwardly rectifying potassium (GIRK) chan...
作者:Shinya Kasai , Junko Hasegawa ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.8 (8)DOAJ
摘要:Individual differences in the sensitivity to fentanyl, a widely used opioid analgesic, lead to different proper doses of fentanyl, which can hamper effective pain treatment. Voltage-activated Ca(2+) channels (VACCs) play a crucial role in the nervous system by controlling membran...
作者:Hirohisa Kojima , Shoko Ieda , Shinya Kasai
来源:[J].Acta Astronautica(IF 0.701), 2014, Vol.101, pp.42-54Elsevier
摘要:Abstract(#br)Underactuated control problems, such as the control of a space robot without actuators on the main body, have been widely investigated. However, few studies have examined attitude control problems of underactuated space robots equipped with a flexible appendage, such...
作者:Shinya Kasai , Hirohisa Kojima , Mitsunori Satoh
来源:[J].Acta Astronautica(IF 0.701), 2013, Vol.84, pp.88-98Elsevier
摘要:Abstract(#br)In this paper, arbitrary rest-to-rest attitude maneuver problems for a satellite using two single-gimbal control moment gyros (2SGCMGs) are considered. Although single-gimbal control moment gyros are configured in the same manner as the traditional pyramid-array CMG,...
作者:Shinya Kasai , Kazutaka Ikeda
来源:[J].Journal of Pain(IF 3.24), 2013, Vol.14 (6), pp.648-661Elsevier
摘要:Abstract(#br)CXBH mice, known as an “opioid receptor-rich” strain, are a recombinant inbred mouse strain established by crossing the C57BL/6By and BALB/cBy strains. In the present study, we investigated nociceptive and antinociceptive sensitivity in CXBH mice and elucidated ...
作者:Shinya Kasai , Ken-ichi Fukuda ...
来源:[J].Neuroscience Letters(IF 2.026), 2013, Vol.542, pp.1-4Elsevier
摘要:Abstract(#br)To elucidate the mechanisms of individual differences in pain and analgesic sensitivity, we analyzed the variable number of tandem repeat polymorphism in the third exon of the dopamine D 4 receptor gene. Alleles that were less than four repeats long and four or more ...
作者:Shinya Kasai , Shinichiro Chuma ...
来源:[J].Developmental Biology(IF 3.868), 2003, Vol.264 (1), pp.202-216Elsevier
摘要:Abstract(#br)In germ cells, the function of which is to form the next generation, apoptotic cell death occurs during development, as in the case of somatic cells. In this study, we show that Bcl-x knockout heterozygous ( Bcl-x +/− ) mice exhibit severe defects in male germ c...

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