全部文献期刊会议图书|学者科研项目
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作者:Shinya Kasai , Miho Tanaka ...
来源:[J].Molecular Brain(IF 4.202), 2017, Vol.10 (1)
摘要:Dopamine is important for motor control and involved in the regulation of circadian rhythm. We previously found that dopamine-deficient (DD) mice became hyperactive in a novel environment 72 h after the last injection of L-3,4-dihydroxyphenylalanine (L-DOPA) when dopamine wa...
作者:Shinya Kasai , Naoki Ogawa ...
来源:[J].Scientific Reports(IF 2.927), 2020, Vol.10 (1), pp.127-138
摘要:Abstract(#br)Magnetic skyrmion is a swirling topological spin texture behaving as an individual particle. It shows a gyro-motion similarly to that of a charged particle under a magnetic field, being led to the transverse shift to the electric current, i.e., skyrmion Hall eff...
作者:Shinya Kasai , Yoshihiko Koukita ...
来源:[J].Journal of Pharmacological Sciences(IF 2.15), 2018, Vol.136 (3), pp.107-113
摘要:Abstract(#br)Opioid analgesics are widely used for the treatment of moderate to severe pain. The analgesic effects of opioids are well known to vary among individuals. The present study focused on the genetic factors that are associated with interindividual differences in pain an...
作者:Shinya Kasai , Yasukazu Ogai ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.4 (9)
摘要:Opioids are commonly used as effective analgesics for the treatment of acute and chronic pain. However, considerable individual differences have been widely observed in sensitivity to opioid analgesics. We focused on a G-protein-activated inwardly rectifying potassium (GIRK) chan...
作者:Shinya Kasai , Junko Hasegawa ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.8 (8)
摘要:Individual differences in the sensitivity to fentanyl, a widely used opioid analgesic, lead to different proper doses of fentanyl, which can hamper effective pain treatment. Voltage-activated Ca(2+) channels (VACCs) play a crucial role in the nervous system by controlling membran...
作者:Shinya Kasai , Junko Hasegawa ...
来源:[J].Journal of Pharmacological Sciences(IF 2.15), 2019, Vol.121 (1), pp.48-57
摘要:Individual differences in the sensitivity to fentanyl, a widely used opioid analgesic, can hamper effective pain treatment. The adrenergic system is reportedly involved in the mechanisms of pain and analgesia. Here, we focused on one of the adrenergic receptor genes, ADRB1, ...
作者:Shinya Kasai , Kaori Yoshida ...
来源:[J].Journal of Pharmacological Sciences(IF 2.15), 2015, Vol.127 (3), pp.391-393
摘要:Abstract(#br)An association between postoperative analgesic requirements in subjects who underwent orthognathic surgery and the rs1465040 single-nucleotide polymorphism close to the transient receptor potential subfamily C member 3 ( TRPC3 ) gene was suggested by our previous gen...
作者:Shinya Kasai , Hirohisa Kojima , Mitsunori Satoh
来源:[J].Acta Astronautica(IF 0.701), 2013, Vol.84, pp.88-98
摘要:Abstract(#br)In this paper, arbitrary rest-to-rest attitude maneuver problems for a satellite using two single-gimbal control moment gyros (2SGCMGs) are considered. Although single-gimbal control moment gyros are configured in the same manner as the traditional pyramid-array CMG,...
作者:Shinya Kasai , Kazutaka Ikeda
来源:[J].Journal of Pain(IF 3.24), 2013, Vol.14 (6), pp.648-661
摘要:Abstract(#br)CXBH mice, known as an “opioid receptor-rich” strain, are a recombinant inbred mouse strain established by crossing the C57BL/6By and BALB/cBy strains. In the present study, we investigated nociceptive and antinociceptive sensitivity in CXBH mice and elucidated ...

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