全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Shintaro Takao , Takeshi Azuma
来源:[J].BMC Cancer(IF 3.333), 2017, Vol.17 (1)Springer
摘要:Triple-negative breast cancer (TN) is more aggressive than other subtypes of breast cancer and has a lower survival rate. Furthermore, detailed biological information about the disease is lacking. This study investigated characteristics of metabolic pathways in TN.
作者:Shintaro Takao , Yasuhisa Yamamoto ...
来源:[J].Investigational New Drugs(IF 3.498), 2017, Vol.35 (6), pp.791-799Springer
摘要:Background This large-scale study was conducted to evaluate the safety and effectiveness of eribulin for the treatment of inoperable or recurrent breast cancer in real-world settings in Japan. Methods Between July and December 2011, eligible patients with inoperable or recur...
作者:Shintaro Takao , Kazuhiko Yamagami ...
来源:[J].Breast Cancer(IF 1.33), 2017, Vol.24 (4), pp.528-534Springer
摘要:Adverse events related to endocrine therapies have a major impact not only on patients’ quality of life but also on treatment discontinuation. Although vasomotor symptoms induced by aromatase inhibitors are frequently recognized, risk factors, especially for Japanese women, ...
作者:Shintaro Takao , Seung Jin Kim ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.10 (12)DOAJ
摘要:Zoledronic acid (ZOL) is a nitrogen-containing bisphosphonate that induces osteoclast apoptosis and inhibits bone resorption by inhibiting the mevalonate pathway. Its benefit for the prevention of skeletal complications due to bone metastases has been established. However, the an...
作者:Shintaro Takao , Kazuhiko Yamagami ...
来源:[J].International Journal of Clinical Oncology(IF 1.727), 2016, Vol.21 (2), pp.262-269Springer
摘要:Abstract(#br) Background(#br)Endocrine treatment-related adverse events have a strong impact on patients’ quality of life and sometimes result in treatment discontinuation. Since joint symptoms are the most frequently recognized side effect of aromatase inhibitors, evaluatio...
作者:Shintaro Takao , Nobuaki Sato ...
来源:[J].Breast Cancer(IF 1.33), 2019, Vol.26 (5), pp.535-543Springer
摘要:Abstract(#br) Background(#br)An association between CYP2D6 polymorphisms and tamoxifen (TAM) efficacy has not been confirmed, partly due to unreliable prediction of active metabolite exposure solely by CYP2D6 activity. The efficacy of TAM dose escalation appears limited in p...
作者:Shintaro Takao , Takahiro Iida ...
来源:[J].Progress in Oceanography(IF 3.708), 2014, Vol.126, pp.233-241Elsevier
摘要:Abstract(#br)The Sea of Okhotsk is one of the most productive ocean regions in the world. However, the in situ bio-optical properties, which are crucial for satellite ocean-color of the productivity, remain uncertain in this region because little data have been available. We...
作者:Shintaro Takao , Toru Hirawake ...
来源:[J].Polar Biology(IF 2.006), 2014, Vol.37 (11), pp.1563-1578Springer
摘要:Abstract(#br)Phytoplankton population dynamics play an important role in biogeochemical cycles in the Southern Ocean during austral summer. However, the relationship between phytoplankton community composition and primary productivity remains elusive in this region. We inves...
作者:Shintaro Takao , Yutaka Tokuda ...
来源:[J].Breast Cancer(IF 1.33), 2012, Vol.19 (4), pp.335-342Springer
摘要:Abstract(#br) Background(#br)Recently gemcitabine has been approved for treatment of metastatic or recurrent breast cancer in Japan; however, no systematically investigated safety study of long-term gemcitabine monotherapy has been reported despite its wide use globally for multi...

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