全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Shinsaku Togo , Ichiro Nagata ...
来源:[J].BMC Cancer(IF 3.333), 2017, Vol.17 (1)Springer
摘要:Receptor for advanced glycation end-products (RAGE), a receptor for amyloids, is constitutively expressed in lungs and generally observed to be downregulated in lung cancer tissues. However, increasing levels of RAGE or serum amyloids is associated with poor outcome in lung cance...
作者:Shinsaku Togo , Miniwan Tulafu ...
来源:[J].Respiratory Research(IF 3.642), 2017, Vol.18 (1)Springer
摘要:Airway fibrosis is one of the pathological features of chronic obstructive pulmonary disease (COPD), and recent studies revealed that acetylcholine plays an important role in the development of airway remodeling by stimulating proliferation and collagen synthesis of lung fib...
作者:Shinsaku Togo , Kotaro Kadoya ...
来源:[J].Respiratory Research(IF 3.642), 2019, Vol.20 (1), pp.1-14DOAJ
摘要:Abstract Background Pirfenidone, an antifibrotic agent used for the treatment of idiopathic pulmonary fibrosis (IPF), functions by inhibiting myofibroblast differentiation, which is involved in transforming growth factor (TGF)-β1-induced IPF pathogenesis. However, unlike nor...
作者:Shinsaku Togo , Tadashi Sato ...
来源:[J].In Vitro Cellular & Developmental Biology - Animal(IF 1.289), 2011, Vol.47 (2), pp.114-124Springer
摘要:Abstract(#br)Fibroblasts are heterogeneous mesenchymal cells that play important roles in the production and maintenance of extracellular matrix. Although their heterogeneity is recognized, progenitor progeny relationships among fibroblasts and the factors that control fibro...
作者:Shinsaku Togo , Hisa Sugiura ...
来源:[J].Experimental Cell Research(IF 3.557), 2010, Vol.316 (20), pp.3501-3511Elsevier
摘要:Abstract(#br)Low concentrations of cigarette smoke induced DNA damage and repair without leading to apoptosis in human bronchial epithelial cells. Higher concentrations of cigarette smoke, however, could induce either apoptosis or necrosis. The current study demonstrated tha...
作者:Shinsaku Togo , Toshibumi Shimokawa ...
来源:[J].FEBS Letters(IF 3.582), 2003, Vol.535 (1), pp.205-209Elsevier
摘要:Abstract(#br)More than 10 splice variants of the Fc receptor for IgA (FcαR, CD89) have been identified in human myeloid cells. In this study, we quantified FcαR splice transcripts ΔEC2 and Δ66EC2, which lack the entire and a part of the homologous immunoglobulin-like extrace...
作者:Shinsaku Togo , Hisatoshi Sugiura ...
来源:[J].The Journal of Allergy and Clinical Immunology(IF 12.047), 2011, Vol.127 (6), pp.1595-1603.e9Elsevier
摘要:Background(#br)Fibroblast heterogeneity is recognized, and fibroblasts from diseased tissues, including those of asthmatic subjects, have functional phenotypes that differ from normal tissue. However, progenitor-progeny relationships and the factors that control fibroblast d...
作者:Shinsaku Togo , Kazue Shimizu ...
来源:[J].Oncology Letters(IF 0.237), 2017, Vol.14 (3), pp.3319-3326Spandidos
摘要:Non‑small cell lung cancer (NSCLC) patients with squamous cell carcinoma(SCC) histology have limited chemotherapeutic options. Treatment with S‑1 combinedwith carboplatin (CBDCA) has been shown to provide a significant survival benefitin SCC patients compared with treatment ...

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