全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Shinji Ohara , Seiji Watanabe ...
来源:[J].Molecular Neurodegeneration(IF 4.007), 2017, Vol.12 (1)Springer
摘要:Dominant mutations in Cu/Zn-superoxide dismutase ( SOD1 ) gene cause a familial form of amyotrophic lateral sclerosis ( SOD1 -ALS) with accumulation of misfolded SOD1 proteins as intracellular inclusions in spinal motor neurons. Oligomerization of SOD1 via abnormal disulfide cros...
作者:Shinji Ohara , Masanobu Yazawa ...
来源:[J].The Cerebellum(IF 2.595), 2017, Vol.16 (2), pp.518-524Springer
摘要:Abstract(#br)Spinocerebellar ataxia type 31 (SCA31) is known as a late-onset, relatively pure cerebellar form of ataxia, but a longitudinal prospective study on the natural history of SCA31 has not been done yet. In this prospective cohort study, we enrolled 44 patients (mea...
作者:... Koichi Kato , Shinji Ohara , Shu-ichi Ikeda
来源:[J].Biological Trace Element Research(IF 1.307), 2017, Vol.175 (1), pp.79-86Springer
摘要:Abstract(#br)The interaction between iron and copper has been discussed in association with human health and diseases for many years. Ceruloplasmin, a multi-copper oxidase, is mainly involved in iron metabolism and its genetic defect, aceruloplasminemia (ACP), shows neurological ...
作者:Shinji Ohara , Yasuko Toyoshima ...
来源:[J].Journal of the Neurological Sciences(IF 2.243), 2014, Vol.339 (1-2), pp.231-234Elsevier
摘要:Abstract(#br)A 63-year-old woman with a past history of right subdural hematoma (SDH) at the age of 61 years was referred to our hospital under a suspicion of aceruloplasminemia (ACP). A neurological examination revealed very mild cognitive impairment and cerebellar ataxia. ...
作者:... Kazuo Kitazawa , Kayoko Higuchi , Shinji Ohara
来源:[J].Journal of the Neurological Sciences(IF 2.243), 2014, Vol.346 (1-2), pp.323-327Elsevier
摘要:Abstract(#br)Acute disseminated encephalomyelitis (ADEM) and multiple sclerosis (MS) are both CNS inflammatory demyelinating diseases with overlapping clinical features. A case is reported of a 51-year-old female who presented with headache, progressive aphasia and hemiparesis wi...

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