全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Shin-Ichi Muramatsu , Kyosuke Uno
来源:[J].PLoS ONE(IF 3.73), 2018, Vol.12 (12)DOAJ
摘要:Transmembrane protein 168 (TMEM168) comprises 697 amino acid residues, including some putative transmembrane domains. It is reported that TMEM168 controls methamphetamine (METH) dependence in the nucleus accumbens (NAc) of mice. Moreover, a strong link between METH dependence-ind...
作者:... Toshihiko Sato , Imaharu Nakano , Shin-ichi Muramatsu
来源:[J].BMC Neurology(IF 2.564), 2011, Vol.11 (1)Springer
摘要:Abstract(#br) Background(#br)In idiopathic Parkinson's disease (PD) the clinical features are heterogeneous and include different predominant symptoms. The aim of the present study was to determine the relationship between subregional aromatic l-amino acid decarboxylase (AAD...
作者:Shin-ichi Muramatsu , Jian-Sheng Gong ...
来源:[J].Journal of Biomedical Science(IF 2.458), 2002, Vol.9 (6), pp.534-541Springer
摘要:Abstract(#br)The restriction endonuclease Sma I has been used for the diagnosis of neurogenic muscle weakness, ataxia and retinitis pigmentosa disease or Leigh's disease, caused by the Mt8993T→G mutation which results in a Leu156Arg replacement that blocks proton translocati...
作者:Shin-ichi Muramatsu , Tatsushi Toda ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.7 (11)DOAJ
摘要:The polyglutamine (polyQ) diseases such as Huntington's disease (HD), are neurodegenerative diseases caused by proteins with an expanded polyQ stretch, which misfold and aggregate, and eventually accumulate as inclusion bodies within neurons. Molecules that inhibit polyQ protein ...
作者:Shin-Ichi Muramatsu , Kenji Sakimura ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.4 (1)DOAJ
摘要:Synchronized discharges in the hippocampal CA3 recurrent network are supposed to underlie network oscillations, memory formation and seizure generation. In the hippocampal CA3 network, NMDA receptors are abundant at the recurrent synapses but scarce at the mossy fiber synapses. W...
作者:Shin-Ichi Muramatsu , Hiroshi Onimaru ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.11 (5)DOAJ
摘要:Despite the strength of the Cre/loxP recombination system in animal models, its application in rats trails that in mice because of the lack of relevant reporter strains. Here, we generated a floxed STOP tdTomato rat that conditionally expresses a red fluorescent protein variant (...
作者:Shin-Ichi Muramatsu , Makoto Takano ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.4 (7)DOAJ
摘要:BACKGROUND: Neurons and glial cells can be efficiently induced from mouse embryonic stem (ES) cells in a conditioned medium collected from rat primary-cultured astrocytes (P-ACM). However, the use of rodent primary cells for clinical applications may be hampered by limited supply...
作者:... Shigeru Yokoyama , Chiharu Tsuji , Shin-ichi Muramatsu
来源:[J].The Journal of Physiological Sciences(IF 1.089), 2017, Vol.67 (1), pp.11-17Springer
摘要:Abstract(#br)We overview the 16-kDa proteolipid mediatophore, the transmembrane c-subunit of the V0 sector of the vacuolar proton ATPase (ATP6V0C) that was shown to mediate the secretion of acetylcholine. Acetylcholine, serotonin, and dopamine (DA) are released from cell soma and...
作者:... Toh Miyazaki , Shin-ichi Muramatsu , Atsumi Nitta
来源:[J].Behavioural Brain Research(IF 3.327), 2019, Vol.376Elsevier
摘要:Abstract(#br)The number of patients with depressive disorders is increasing. However, the mechanism of depression onsets has not been completely revealed. We previously identified Shati/Nat8l, an N -acetyltransferase, in the brain using an animal model of psychosis. In this study...

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