全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Shin Nishiumi , Seishi Kono ...
来源:[J].BMC Cancer(IF 3.333), 2017, Vol.17 (1)Springer
摘要:Triple-negative breast cancer (TN) is more aggressive than other subtypes of breast cancer and has a lower survival rate. Furthermore, detailed biological information about the disease is lacking. This study investigated characteristics of metabolic pathways in TN.
作者:Shin Nishiumi , Masaru Yoshida
来源:[J].Gut Pathogens(IF 2.738), 2017, Vol.9 (1)Springer
摘要:Helicobacter pylori infection is associated with risk for chronic gastritis (CG), gastric ulcer (GU), duodenal ulcer (DU), and gastric cancer (GC). The H. pylori Cag type IV secretion system (TFSS) translocates the virulence factor cytotoxin-associated gene A protein into host ce...
作者:Shin Nishiumi , Takashi Kobayashi ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.7 (7)DOAJ
摘要:To improve the quality of life of colorectal cancer patients, it is important to establish new screening methods for early diagnosis of colorectal cancer.We performed serum metabolome analysis using gas-chromatography/mass-spectrometry (GC/MS). First, the accuracy of our GC/MS-ba...
作者:Shin Nishiumi , Yasuyuki Kondo ...
来源:[J].International Journal of Molecular Sciences(IF 2.464), 2011, Vol.12 (2), pp.1115DOAJ
摘要:Previously, we reported that vitamin K3 (VK3), but not VK1 or VK2 (=MK-4), inhibits the activity of human DNA polymerase γ (pol γ). In this study, we chemically synthesized three intermediate compounds between VK2 and VK3, namely MK-3, MK-2 and MK-1, and investigated the inh...
作者:Shin Nishiumi , Yoshihiro Izumi , Masaru Yoshida
来源:[J].Digestive Diseases and Sciences(IF 2.26), 2018, Vol.63 (6), pp.1485-1496Springer
摘要:Abstract(#br) Background(#br)Inflammatory bowel disease (IBD) is an intestinal disorder, involving chronic and relapsing inflammation of the digestive tract. Dysregulation of the immune system based on genetic, environmental, and other factors seems to be involved in the ons...
作者:Shin Nishiumi , Masayuki Nishida ...
来源:[J].International Journal of Molecular Sciences(IF 2.464), 2011, Vol.12 (2), pp.1115-1132DOAJ
摘要:Previously, we reported that vitamin K3 (VK3), but not VK1 or VK2 (=MK-4), inhibits the activity of human DNA polymerase γ (pol γ). In this study, we chemically synthesized three intermediate compounds between VK2 and VK3, namely MK-3, MK-2 and MK-1, and investigated the inh...
作者:Shin Nishiumi , Makoto Ooi ...
来源:[J].Journal of Crohn's and Colitis(IF 3.385), 2014, Vol.8 (9), pp.1010-1021Elsevier
摘要:Abstract(#br)Background & aims(#br)To improve the clinical course of ulcerative colitis (UC), more accurate serum diagnostic and assessment methods are required. We used serum metabolomics to develop diagnostic and assessment methods for UC.(#br)Methods(#br)Sera from UC patients,...
作者:Shin Nishiumi , Naoki Fujitsuka ...
来源:[J].Evidence-Based Complementary and Alternative Medicine(IF 1.722), 2015, Vol.2015Hindawi
摘要:Cancer cachexia, which is characterized by decreased food intake, weight loss and systemic inflammation, increases patient’s morbidity and mortality. We previously showed that rikkunshito (RKT), a Japanese traditional herbal medicine (Kampo), ameliorated the symptoms of canc...
作者:Shin Nishiumi , Takashi Kobayashi ...
来源:[J].Metabolomics(IF 4.433), 2016, Vol.12 (4)Springer
摘要:Abstract(#br) Introduction(#br)The adenomatous polyposis coli ( APC ) gene is a tumor suppressor gene that is inactivated in the initiation of colorectal neoplasia. Apc Min /+ mice, which possess a heterozygous APC mutation, develop numerous adenomatous polyps, which ...
作者:Shin Nishiumi , Keisuke Shima ...
来源:[J].Journal of Bioscience and Bioengineering(IF 1.737), 2017, Vol.123 (6), pp.754-759Elsevier
摘要:Metabolomics has recently been developed, and there have been a considerable number of metabolomics-based biomarker studies in the medical research field. Therefore, as a first step toward the practical use of metabolite biomarkers, a simple and quick sample preparation method in...

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