全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Shih-Hsin Tu , Yi-Chen Hsieh ...
来源:[J].BMC Cancer(IF 3.333), 2017, Vol.17 (1)Springer
摘要:As cancer metastasis is the deadliest aspect of cancer, causing 90% of human deaths, evaluating the molecular mechanisms underlying this process is the major interest to those in the drug development field. Both therapeutic target identification and proof-of-concept experimentati...
作者:Shih-Hsin Tu , Chien-Tien Su ...
来源:[J].Breast Cancer Research and Treatment(IF 4.469), 2017, Vol.163 (1), pp.131-138Springer
摘要:Multiple common variants identified by genome-wide association studies showed limited evidence of the risk of breast cancer in Taiwan. In this study, we analyzed the breast cancer risk in relation to 13 individual single-nucleotide polymorphisms (SNPs) identified by a GWAS in an ...
作者:Shih-Hsin Tu , Heng-Hui Lien ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.8 (10)DOAJ
摘要:The interplay between copy number variation (CNV) and differential gene expression may be able to shed light on molecular process underlying breast cancer and lead to the discovery of cancer-related genes. In the current study, genes concurrently identified in array comparative g...
作者:Shih-Hsin Tu , Hsiu-Man Lien ...
来源:[J].Journal of Cancer Research and Therapeutics(IF 0.761), 2012, Vol.8 (4), pp.532-536DOAJ
摘要:Context: The compound 4,7-dimethoxy-5-(2-propen-1-yl)-1,3-benzodioxole (apiole) has been isolated from several different plant species, including Petroselinum sativum. Our recent study found that apiole is a chemical derivative of 4,7-dimethoxy-5-methyl-l,3-benzodioxole (SY-...
作者:Shih-Hsin Tu , Heng-Hui Lien ...
来源:[J].Quality of Life Research(IF 2.412), 2015, Vol.24 (8), pp.1999-2013Springer
摘要:Abstract(#br) Objective(#br)This study aimed to evaluate the conceptual structure of the European Organization for Research and Treatment of Cancer Quality of Life Core Questionnaire 30 (EORTC QLQ-C30) by analyzing data collected from patients with major cancers in Taiwan. T...
作者:Shih-Hsin Tu , Heng-Hui Lien ...
来源:[J].Breast Cancer Research and Treatment(IF 4.469), 2014, Vol.147 (2), pp.353-370Springer
摘要:Abstract(#br)Several prognostic signatures have been identified for breast cancer. However, these signatures vary extensively in their gene compositions, and the poor concordance of the risk groups defined by the prognostic signatures hinders their clinical applicability. Br...
作者:Shih-Hsin Tu , Li-Ching Chen ...
来源:[J].Human Pathology(IF 2.843), 2018Elsevier
摘要:Summary(#br)The transcription factor GATA3 plays a significant role in mammary gland development and differentiation. We analyzed expression of GATA3 in breast cancer (BC) cell lines and clinical specimens from BC patients in Taiwan. Semi-quantitative reverse transcriptase (...
作者:Shih-Hsin Tu , Ching-Shui Huang ...
来源:[J].Breast Cancer Research and Treatment(IF 4.469), 2012, Vol.134 (3), pp.989-1004Springer
摘要:Abstract(#br)The extracellular matrix (ECM) plays a critical role in the development and invasion of primary breast tumors. Lysyl oxidase (LOX), which is an ECM remodeling enzyme, appears to play roles in promoting cancer cell motility and invasion. To ascertain whether LOX ...
作者:Shih-Hsin Tu , Li-Ching Chen , Yuan-Soon Ho
来源:[J].Journal of Food and Drug Analysis(IF 0.333), 2016Elsevier
摘要:Abstract(#br)The purpose of this review is to update and discuss key findings from in vitro and in vivo studies on apple and its biocompounds, with a special focus on its anticancer role. Several studies have proposed that apple and its extracts exhibit a variety of biological fu...
作者:Shih-Hsin Tu , Chih-Hsiung Wu ...
来源:[J].Molecular Cell(IF 15.28), 2015, Vol.58 (6), pp.989-1000Elsevier
摘要:Summary(#br)The regulation of RagA GTP is important for amino-acid-induced mTORC1 activation. Although GATOR1 complex has been identified as a negative regulator for mTORC1 by hydrolyzing RagA GTP , how GATOR1 is recruited to RagA to attenuate mTORC1 signaling remains unclear. Mo...

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