全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:... Gyu Hwan Park , Seong-Ryong Lee , Jung-Hee Jang
来源:[J].Oxidative Medicine and Cellular Longevity(IF 3.393), 2013, Vol.2013DOAJ
摘要:β-amyloid peptide (Aβ), a major component of senile plaques, plays important roles in neuropathology of Alzheimer's disease (AD). An array of in vitro and in vivo data indicates that Aβ-induced neuronal death is mediated by oxidative stress. In this study, we aimed to invest...
作者:Su-Jin Kim , Seong-Ryong Lee
来源:[J].Life Sciences(IF 2.555), 2014, Vol.94 (1), pp.8-16Elsevier
摘要:Abstract(#br)Aims(#br)Melatonin possesses various pharmacological effects including neuroprotective effects against brain ischemia. Post-ischemic increases in matrix metalloproteinase-9 (MMP-9) expression and activity mainly contribute to neuronal damage by degradation of the ext...
作者:Jeong-Ho Hong , Hyung Lee , Seong-Ryong Lee
来源:[J].The Journal of Nutritional Biochemistry(IF 4.552), 2016, Vol.27, pp.146-152Elsevier
摘要:Abstract(#br)Resveratrol (3,5,4'-trihydroxystilbene) is a natural polyphenol which is rich in grape seeds and skin. Several studies have revealed that resveratrol possesses neuroprotective effects. In the case of global brain ischemia, there are few reports regarding the protecti...
作者:Seong-Ryong Lee , Hahn-Young Kim ...
来源:[J].Biochemical and Biophysical Research Communications(IF 2.406), 2008, Vol.380 (1), pp.17-21Elsevier
摘要:Abstract(#br)Pioglitazone, a peroxisome proliferator-activated receptor gamma (PPARγ) agonist, has shown protective effects against ischemic insult in various tissues. Pioglitazone is also reported to reduce matrix metalloproteinase (MMP) activity. MMPs can remodel extracell...
作者:Seong-Ryong Lee , Sang-Pyo Kim , Ji-Eun Kim
来源:[J].Neuroscience Letters(IF 2.026), 2000, Vol.281 (2), pp.183-186Elsevier
摘要:Abstract(#br)The purpose of this study was to examine whether topiramate would reduce neuronal damage after transient global ischemia in the gerbils because topiramate blocks voltage sensitive sodium channels and non- N -methyl- d -aspartate receptors and enhances γ-aminobut...
作者:Seong-Ryong Lee , Seong-Il Suh , Sang-Pyo Kim
来源:[J].Neuroscience Letters(IF 2.026), 2000, Vol.287 (3), pp.191-194Elsevier
摘要:Abstract(#br)Recent studies have shown that green tea polyphenols reduce free radical-induced lipid peroxidation. Oxygen free radical injury plays an important role in neuronal damage induced by brain ischemia and reperfusion. The purpose of this study was to examine whether...

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