全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Selma Topçu , Carine Marinach ...
来源:[J].Cell Host & Microbe(IF 12.609), 2015, Vol.18 (5), pp.593-603Elsevier
摘要:Summary(#br)Plasmodium sporozoites are deposited in the host skin by Anopheles mosquitoes. The parasites migrate from the dermis to the liver, where they invade hepatocytes through a moving junction (MJ) to form a replicative parasitophorous vacuole (PV). Malaria sporozoites need...
作者:Selma Topçu , Isabelle Dugail ...
来源:[J].Journal of Autoimmunity(IF 8.145), 2012, Vol.39 (3), pp.168-172Elsevier
摘要:Abstract(#br)Intravenous immunoglobulin (IVIg) is a therapeutic preparation consisting of pools of normal, polyspecific IgG antibodies obtained from plasma of several thousand healthy individuals. In addition to its use in primary and secondary immune deficiency, IVIg is increasi...
作者:Selma Topçu , Chaitrali Saha ...
来源:[J].European Journal of Immunology(IF 4.97), 2014, Vol.44 (7), pp.2059-2063Wiley
摘要:Several mechanisms account for the beneficial effect of intravenous immunoglobulin (IVIg) in autoimmune and inflammatory diseases. These mechanisms include effects on the cellular compartment and on the humoral compartment. Thus, IVIg impacts on dendritic cells, macrophages,...
作者:Selma Topçu , Olivia Son ...
来源:[J].Cellular Microbiology(IF 4.811), 2014, Vol.16 (10), pp.1533-1548Wiley
摘要:Summary(#br)P lasmodium sporozoites are transmitted by A nopheles mosquitoes and first infect the liver of their mammalian host, where they develop as liver stages before the onset of erythrocytic infection and malaria symptoms. Sporozoite entry into hepatocytes is an attrac...
作者:Selma Topçu , Lakhdar Fattoum ...
来源:[J].PLOS ONE(IF 3.73), 2011, Vol.6 (10)PLOS
摘要:Polymorphonuclear neutrophils (PMN) play a key role in host defences against invading microorganisms but can also potentiate detrimental inflammatory reactions in case of excessive or misdirected responses. Intravenous immunoglobulins (IVIg) are used to treat patients with immune...
作者:Selma Topçu , Sylvie Briquet ...
来源:[J].eLife, 2017, Vol.6eLife科学出版社
摘要:Plasmodium sporozoites, the mosquito-transmitted forms of the malaria parasite, first infect the liver for an initial round of replication before the emergence of pathogenic blood stages. Sporozoites represent attractive targets for antimalarial preventive strategies, yet the mec...

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