全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Machida C M , Scott J D , Ciment G
来源:[J].The Journal of cell biology(IF 10.822), 1991, Vol.114 (5), pp.1037-48PubMed
摘要:In previous work, we found that nerve growth factor (NGF) induced expression of the mRNA transcript encoding the metalloproteinase transin/stromelysin in PC12 cells. Transin was found, moreover, to be a "late" gene product whose expression correlated with neurites extension. In t...
作者:Scott J D , Jahnsen T
来源:[J].Experimental cell research(IF 3.557), 1998, Vol.238 (2), pp.305-16PubMed
摘要:The cyclic AMP-dependent protein kinase (PKA) type II is directed to different subcellular loci through interaction of the RII subunits with A-kinase anchoring proteins (AKAPs). A full-length human clone encoding AKAP95 was identified and sequenced, and revealed a 692-amino acid ...
作者:Schillace R V , Scott J D
来源:[J].Current biology : CB(IF 9.494), 1999, Vol.9 (6), pp.321-4PubMed
摘要:The cyclic AMP (cAMP)-dependent protein kinase (PKA) and the type 1 protein phosphatase (PP1) are broad-specificity signaling enzymes with opposing actions that catalyze changes in the phosphorylation state of cellular proteins. Subcellular targeting to the vicinity of preferred ...
作者:... Schillace R V , Westphal A M , Scott J D
来源:[J].Journal of cell science(IF 5.877), 1999, Vol.112 ( Pt 1, pp.2725-36PubMed
摘要:The compartmentalization of second messenger-activated protein kinases contributes to the fidelity of hormone-mediated signal transduction events. For example, the cAMP-dependent protein kinase is tethered at specific intracellular locations through association with A-kinase anch...
作者:... Coghlan V M , Nauert B , Scott J D
来源:[J].The Journal of biological chemistry(IF 4.651), 1996, Vol.271 (16), pp.9460-5PubMed
摘要:Compartmentalization of the type II cyclic AMP-dependent kinase (PKA) is achieved through association of the regulatory subunit (RII) with A-kinase anchoring proteins (AKAPs). Using an interaction cloning strategy with RIIalpha as a probe, we have isolated cDNAs encoding a novel ...
作者:Scott J D , Jahnsen T
来源:[J].Experimental cell research(IF 3.557), 1994, Vol.214 (2), pp.595-605PubMed
摘要:The human regulatory subunit RI beta of cAMP-dependent protein kinases was expressed in Escherichia coli as a fusion protein with glutathione S-transferase. Purification was performed by affinity chromatography on glutathione-agarose beads after cleavage with thrombin. The human ...
作者:Scott J D , Fernando K ...
来源:[J].Journal of Medical Entomology(IF 1.857), 2001, Vol.38 (4), pp.493-500PubMed
摘要:A total of 152 ixodid ticks (Acari: Ixodidae) consisting of nine species was collected from 82 passerine birds (33 species) in 14 locations in Canada from 1996 to 2000. The Lyme disease spirochete Borrelia burgdorferi Johnson, Schmidt, Hyde, Steigerwaldt & Brenner was cultured fr...
作者:Scott J D , Forrest A ...
来源:[J].Infection Control & Hospital Epidemiology(IF 4.02), 2001, Vol.22 (6), pp.347-51PubMed
摘要:We have developed and analyzed a large surgical prophylaxis database and now report the factors significantly associated with early infection, readmission due to infection, and death within 28 days of surgery. This study is intended to be a stepping-stone for further studies usin...

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