全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Sanghoon Moon , Longfei Wang ...
来源:[J].BMC Bioinformatics(IF 3.024), 2017, Vol.18 (1)Springer
摘要:Copy number variation (CNV) is known to play an important role in the genetics of complex diseases and several methods have been proposed to detect association of CNV with phenotypes of interest. Statistical methods for CNV association analysis can be categorized into two differe...
作者:Sanghoon Moon , Yun Kyoung Kim ...
来源:[J].Journal of Genetics(IF 0.876), 2017, Vol.96 (6), pp.1041-1046Springer
摘要:Myocardial infarction (MI) is a complex disease caused by combination of genetic and environmental factors. Although genome-wide association studies (GWAS) identified more than 46 risk loci which are associated with coronary artery disease and MI, most of the genetic variability ...
作者:Sanghoon Moon , Bhumsuk Keam ...
来源:[J].BMC Musculoskeletal Disorders(IF 1.875), 2015, Vol.16 (1)Springer
摘要:Abstract(#br) Background(#br)OA is a complex disease caused by environmental and genetic risk factors. The purpose of this study is to identify candidate copy number variations (CNVs) associated with OA.(#br) Methods(#br)We performed a genome-wide association study of CNV to...
作者:Sanghoon Moon , Young Jin Kim ...
来源:[J].Scientific Reports(IF 2.927), 2019, Vol.9 (1), pp.1-11DOAJ
摘要:Abstract We introduce the design and implementation of a new array, the Korea Biobank Array (referred to as KoreanChip, optimized for the Korean population and demonstrate findings from GWAS of blood biochemical traits. KoreanChip comprised >833,000 markers including >247,00...
作者:Sanghoon Moon , Sohee Han
来源:[J].Cardiovascular Diabetology(IF 4.209), 2016, Vol.15 (1)Springer
摘要:Abstract(#br) Background(#br)The genetic contribution to complex diseases or traits, including cardio-metabolic traits, has been elucidated recently by large-scale genome-wide association studies. These genome-wide association studies have indicated that most pleiotropic loc...
作者:Sanghoon Moon , Juyoung Lee ...
来源:[J].International Journal of Environmental Research and Public Health(IF 1.998), 2014, Vol.11 (12), pp.12283-12303DOAJ
摘要:Longitudinal data enables detecting the effect of aging/time, and as a repeated measures design is statistically more efficient compared to cross-sectional data if the correlations between repeated measurements are not large. In particular, when genotyping cost is more expensive ...
作者:Sanghoon Moon , Jun Ho Yun ...
来源:[J].Genomics(IF 3.01), 2014, Vol.104 (2), pp.113-120Elsevier
摘要:Abstract(#br)Copy number variations (CNVs) have emerged as another important genetic marker in addition to SNP for understanding etiology of complex diseases. In light of this, we performed a genome-wide CNV study to identify type 2 diabetes (T2D)-associated CNV using an arr...
作者:Sanghoon Moon , Lyong Heo ...
来源:[J].Genomics(IF 3.01), 2015, Vol.105 (3), pp.145-149Elsevier
摘要:Abstract(#br)Copy number variations (CNVs) are known risk factors in complex diseases. Array-based approaches have been widely used to detect CNVs, but limitations of array-based CNV detection methods, such as noisy signal and low resolution, have hindered detection of small...
作者:Sanghoon Moon , Mi Yeong Hwang ...
来源:[J].Genomics(IF 3.01), 2012Elsevier
摘要:Abstract(#br)Height is a classic polygenic trait with high heritability (h 2 = 0.8). Recent genome-wide association studies have revealed many independent loci associated with human height. In addition, although many studies have reported an association between copy number varia...

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