全部文献期刊会议图书|学者科研项目
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作者:Sandra Fernezlian , Vanessa Karen de Sá ...
来源:[J].Journal of Controlled Release(IF 7.633), 2014, Vol.180, pp.125-133Elsevier
摘要:Abstract(#br)Thymulin has been shown to present anti-inflammatory and anti-fibrotic properties in experimental lung diseases. We hypothesized that a biologically active thymulin analog gene, methionine serum thymus factor, delivered by highly compacted DNA nanoparticles may preve...
作者:Sandra Fernezlian , Edwin Roger Parra ...
来源:[J].Respiratory Physiology & Neurobiology(IF 2.051), 2013, Vol.189 (3), pp.614-623Elsevier
摘要:Abstract(#br)We analyzed the effects of different administration routes and application times of the BCG-Moreau strain on airway and lung inflammation and remodeling in a murine model of allergic asthma. BALB/c mice ( n = 168) were divided into two groups. The first group receiv...
作者:Sandra Fernezlian , Adri Mulder ...
来源:[J].The Journal of Allergy and Clinical Immunology(IF 12.047), 2009, Vol.123 (5), pp.1090-1097.e1Elsevier
摘要:Background(#br)Structural and inflammatory changes in asthma involve both the large and small airways, with involvement of the distal lung being related to disease severity. We have previously shown that changes in the extracellular matrix (ECM) composition of the distal lung are...
作者:Sandra Fernezlian , Carlos Roberto Ribeiro de Carvalho ...
来源:[J].Human Pathology(IF 2.843), 2010, Vol.41 (3), pp.385-391Elsevier
摘要:Summary(#br)Idiopathic pulmonary fibrosis is a distinctive, usually fatal, type of chronic fibrosing interstitial pneumonia of unknown cause that increases in prevalence with advanced age, characterized by failure of alveolar re-epithelization and progressive scar formation. Rece...
作者:Sandra Fernezlian , Alexandre Muxfeldt Ab'Saber ...
来源:[J].Human Pathology(IF 2.843), 2009, Vol.41 (2), pp.239-248Elsevier
摘要:Summary(#br)Collagen V shows promise as an inducer of the death response via caspases. Remodeling of the microenvironment by collagen V, tumoral/vascular apoptosis, and the immune response were evaluated, based on the prognosis of 65 patients with surgically excised non-small cel...
作者:Sandra Fernezlian , Jasmijn A Schrumpf ...
来源:[J].The Journal of Pathology(IF 7.585), 2005, Vol.207 (1), pp.102-110Wiley
摘要:Abstract(#br)It has been suggested that airway remodelling is responsible for the persistent airway obstruction and decline in lung function observed in some asthmatic patients. The small airways are thought to contribute significantly to this functional impairment. Proteogl...
作者:Sandra Fernezlian , Ana L. Garippo ...
来源:[J].Pediatric Pulmonology(IF 2.375), 2004, Vol.38 (3), pp.233-239Wiley
摘要:Abstract(#br)Childhood bronchiolitis obliterans (CBO) is an infrequent, severe disorder characterized by persistent obstructive respiratory symptoms after an acute episode of bronchiolitis. The viral etiology is most common, and adenovirus is the most frequently identified c...
作者:... João Valente Barbas-Filho , Sandra Fernezlian , Vera Luiza Capelozzi
来源:[J].Clinics, 2012, Vol.67 (9), pp.1039-1046DOAJ
摘要:OBJECTIVE: This study sought to identify the relationship between fibroblast telomerase expression, myofibroblasts, and telomerase-mediated regulatory signals in idiopathic pulmonary fibrosis. METHODS: Thirty-four surgical lung biopsies, which had been obtained from patients...

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