全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:... Teresa Gasalla , Sami Elmoufti , Jan-Peer Elshoff
来源:[J].European Journal of Paediatric Neurology(IF 1.982), 2019Elsevier
摘要:Abstract(#br)Objective(#br)To evaluate long-term safety and tolerability of adjunctive brivaracetam (BRV) in children with epilepsy.(#br)Methods(#br)This was an interim analysis (cut-off March 15, 2017) of pooled data from two open-label, single-arm, multicentre trials. N012...
作者:Sami Elmoufti , Jimmy Schiemann
来源:[J].Epilepsy Research(IF 2.241), 2017, Vol.131, pp.70-75Elsevier
摘要:Abstract(#br)Brivaracetam (BRV), a selective, high-affinity ligand for synaptic vesicle protein 2A, is a new antiepileptic drug (AED) for adjunctive treatment of focal (partial-onset) seizures in adults with epilepsy. This post-hoc analysis was conducted to explore the effic...
作者:... Armel Stockis , Sami Elmoufti , John Whitesides
来源:[J].Epilepsy Research(IF 2.241), 2018, Vol.145, pp.55-62Elsevier
摘要:Abstract(#br)To assess the association, if any, between brivaracetam (BRV)-induced elevated carbamazepine-10,11-epoxide (CBZ-E) and toxicity and efficacy in patients with epilepsy. Data were pooled from three double-blind, placebo-controlled, Phase III studies of adjunctive ...
作者:... Anyzeila Diaz , Sami Elmoufti , John Whitesides
来源:[J].Epilepsy & Behavior(IF 1.844), 2018, Vol.80, pp.129-134Elsevier
摘要:Abstract(#br)Objective(#br)The objective was to assess the efficacy and safety of adjunctive brivaracetam (BRV) with concomitant use of lamotrigine (LTG) or topiramate (TPM) in patients with uncontrolled focal seizures.(#br)Methods(#br)Data were pooled from three randomized,...
作者:Sami Elmoufti , Knut Mueller ...
来源:[J].Epilepsy & Behavior(IF 1.844), 2016Elsevier
摘要:Abstract(#br)Purpose(#br)The effect of adjunctive brivaracetam on health-related quality of life (HRQoL) was assessed in a post-hoc analysis using pooled data from three randomized, double-blind, placebo-controlled Phase III studies in patients with refractory focal seizures...
作者:Sami Elmoufti , Peter Dedeken ...
来源:[J].Epilepsy & Behavior(IF 1.844), 2016, Vol.62, pp.1-5Elsevier
摘要:Abstract(#br)Treatment with enzyme-inducing antiepileptic drugs (AEDs) such as carbamazepine (CBZ) can lead to changes in reproductive, endocrine, and lipid parameters, resulting in clinical symptoms for some patients. Previous studies indicate that these changes can be reve...

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