全部文献期刊会议图书|学者科研项目
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作者:Sabrina Giacoppo , Thangavelu Soundara Rajan ...
来源:[J].Inflammation Research(IF 1.964), 2017, Vol.66 (6), pp.487-503
摘要:In the last decades, a growing need to discover new compounds for the prevention and treatment of inflammatory diseases has led researchers to consider drugs derived from natural products as a valid option in the treatment of inflammation-associated disorders. The purpose of...
作者:Sabrina Giacoppo , Placido Bramanti , Emanuela Mazzon
来源:[J].Archivum Immunologiae et Therapiae Experimentalis(IF 2.378), 2017, Vol.65 (5), pp.363-379
摘要:In recent years, in the effort to find a potential innovative therapy for multiple sclerosis (MS), researchers focused on transplantation of mesenchymal stem cells (MSCs) due to their well-recognized ability to suppress inflammatory/autoimmune responses and exert neuroregenerativ...
作者:Sabrina Giacoppo , Renato Iori ...
来源:[J].BMC Complementary and Alternative Medicine(IF 2.082), 2017, Vol.17 (1)
摘要:Several lines of evidence suggest the consume of natural products for cancer prevention or treatment. In particular, isothiocyanates (ITCs) exerting anti-cancer properties, have received great interest as potential chemotherapeutic agents.
作者:Sabrina Giacoppo , Oxana Bereshchenko ...
来源:[J].Neuroscience Letters(IF 2.026), 2017, Vol.653, pp.159-162
摘要:Abstract(#br)Primary progressive multiple sclerosis (PP-MS) is a less common progressive form of MS in approximately 10% of patients that manifest increasingly neurological disability from disease onset. To date, there are no approved treatments for the progressive stage. Th...
作者:Sabrina Giacoppo , Maria Galuppo ...
来源:[J].Bioorganic & Medicinal Chemistry(IF 2.903), 2015, Vol.23 (1), pp.80-88
摘要:Abstract(#br)4(α- l -Rhamnosyloxy)-benzyl isothiocyanate (glucomoringin isothiocyanate; GMG-ITC) is released from the precursor 4(α- l -rhamnosyloxy)-benzyl glucosinolate (glucomoringin; GMG) by myrosinase (β-thioglucoside glucohydrolase; E.C. 3.2.1.147) catalyzed hydrolysis...
作者:Sabrina Giacoppo , Oriana Trubiani ...
来源:[J].Experimental Cell Research(IF 3.557), 2016, Vol.349 (1), pp.152-161
摘要:Abstract(#br)Conditioned medium derived from mesenchymal stem cells (MSCs) shows immunomodulatory and neuroprotective effects in preclinical models. Given the difficulty to harvest MSCs from bone marrow and adipose tissues, research has been focused to find alternative resou...
作者:Sabrina Giacoppo , Simona Pace ...
来源:[J].Pharmacological Research(IF 4.346), 2015, Vol.99, pp.316-328
摘要:Abstract(#br)Traumatic spinal cord injury (SCI) represents one of the most disabling injuries of the human body causing temporary or permanent sensory and/or motor system deficit, particularly hind limb locomotor function impairment. At present, steroidal inflammatory drugs, in p...
作者:Sabrina Giacoppo , Emanuela Mazzon
来源:[J].Neural Regeneration Research(IF 0.144), 2016, Vol.11 (12), pp.1896-1899
摘要:Amyotrophic lateral sclerosis (ALS) is the most common degenerative disease of the motor neuron system. Over the last years, a growing interest was aimed to discovery new innovative and safer therapeutic ap-proaches in the ALS treatment. In this context, the bioactive compounds o...
作者:Sabrina Giacoppo , Maria Galuppo ...
来源:[J].DARU Journal of Pharmaceutical Sciences, 2015, Vol.23 (1)
摘要:Abstract(#br) Background(#br)The present study was designed to investigate the efficacy of a new formulation of alone, purified cannabidiol (CBD) (>98 %), the main non-psychotropic cannabinoid of Cannabis sativa, as a topical treatment in an experimental model of autoimmune ...
作者:Sabrina Giacoppo , Francesca Diomede ...
来源:[J].Scientific Reports(IF 2.927), 2016, Vol.6 (1), pp.2329-2343
摘要:Abstract(#br)Manipulation of stem cells or stem cells-derived secretome has emerged as a novel alternative therapeutic option for multiple sclerosis (MS). Here we show that human periodontal ligament stem cells (hPDLSCs)-derived conditioned medium (hPDLSCs-CM) and purified e...

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