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作者:... Attila Kertész-Farkas , Dóra Szabó , Sándor Pongor
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.9 (4)
摘要:Multispecies bacterial communities such as the microbiota of the gastrointestinal tract can be remarkably stable and resilient even though they consist of cells and species that compete for resources and also produce a large number of antimicrobial agents. Computational modeling ...
作者:Sándor Pongor , Antonella Campanella ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.7 (1)
摘要:The crustacean Hyperglycemic Hormone (cHH) is present in many decapods in different isoforms, whose specific biological functions are still poorly understood. Here we report on the first chemical synthesis of three distinct isoforms of the cHH of Astacus leptodactylus carrie...
作者:... Adám Kerényi , Sergiu Netotea , Sándor Pongor
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.5 (4)
摘要:BACKGROUND: Members of swarming bacterial consortia compete for nutrients but also use a co-operation mechanism called quorum sensing (QS) that relies on chemical signals as well as other secreted products ("public goods") necessary for swarming. Deleting various genes of this ma...
作者:... Roberto Vera , Balázs Győrffy , Sándor Pongor
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.10 (6)
摘要:Drug combinations are highly efficient in systemic treatment of complex multigene diseases such as cancer, diabetes, arthritis and hypertension. Most currently used combinations were found in empirical ways, which limits the speed of discovery for new and more effective combinati...
作者:... Dóra Bihary , Vittorio Venturi , Sándor Pongor
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.8 (3)
摘要:Multispecies bacterial communities can be remarkably stable and resilient even though they consist of cells and species that compete for environmental resources. In silico models suggest that common signals released into the environment may help selected bacterial species cluster...
作者:Sándor Pongor , László Nagy
来源:[J].BMC Genomics(IF 4.397), 2016, Vol.17 (1)
摘要:Abstract(#br) Background(#br)ChIP-seq provides a wealth of information on the approximate location of DNA-binding proteins genome-wide. It is known that the targeted motifs in most cases can be found at the peak centers. A high resolution mapping of ChIP-seq peaks could in p...
作者:... Ventsislav Zlatev , Sándor Pongor , Alessandro Pintar
来源:[J].Biochemical and Biophysical Research Communications(IF 2.406), 2013, Vol.432 (4), pp.666-671
摘要:Abstract(#br)Ectodomain shedding of membrane receptors and ligands carried out by ADAMs (A disintegrin and metalloprotease) plays a major role in several signaling pathways, including Notch. The grounds of substrate recognition, however, are poorly understood. We demonstrate that...
作者:... Subbiah Parthasarathy , István Simon , Sándor Pongor
来源:[J].Trends in Biochemical Sciences(IF 13.076), 1998, Vol.23 (9), pp.341-347
摘要:Abstract(#br)Local bending phenomena can be predicted by elastic models that incorporate sequence-dependent anisotropic-bendability (SDAB). SDAB models consider DNA to be an initially straight, segmented, elastic rod, in which the flexibility of each segment is greater towards th...
作者:Oliviero Carugo , Sándor Pongor
来源:[J].Trends in Biotechnology(IF 9.66), 2002, Vol.20 (12), pp.498-501
摘要:Abstract(#br)Starting with the Protein Data Bank (PDB) as a common ancestor, the evolution of structural databases has been driven by the rapprochement of the structural world and the practical applications. The result is an impressive number of secondary structural databases tha...
作者:Sergiu Netotea , Sándor Pongor
来源:[J].Cellular Immunology(IF 1.743), 2006, Vol.244 (2), pp.80-83
摘要:Abstract(#br)Mutation/selection algorithms were applied to increase the efficiency and the robustness of sparse random networks. Selection for better efficiency leads to the well-known star topology, while selection for robustness only results in a relatively dense core and a sma...

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