全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:... David F. McDermott , Sabina Signoretti , Rupal S. Bhatt
来源:[J].Clinical Genitourinary Cancer(IF 1.429), 2018Elsevier
摘要:Abstract(#br)Introduction(#br)Genomic events leading to activation of mechanistic target of rapamycin (mTOR) are common in renal cell carcinoma (RCC). Everolimus is an allosteric mTOR inhibitor with efficacy in metastatic RCC. We characterized the genomic profile of RCC tumo...
作者:Rupal S. Bhatt , Jiaxi Song ...
来源:[J].Clinical Genitourinary Cancer(IF 1.429), 2016, Vol.14 (4), pp.304-313.e6Elsevier
摘要:Abstract(#br)Background(#br)Inhibiting VEGF and mammalian target of rapamycin (mTOR) pathways are standard treatment approaches for patients with metastatic renal cell carcinoma (mRCC). Here we report the activity and safety of the VEGF ligand inhibitor bevacizumab and the mTOR i...
作者:Rupal S. Bhatt , Michael B. Atkins
来源:[J].Clinical Genitourinary Cancer(IF 1.429), 2014, Vol.12 (1), pp.55-62Elsevier
摘要:Abstract(#br)Objective(#br)The study objective was to correlate the magnetic resonance imaging (MRI) features of clear cell renal cell carcinoma (ccRCC) with the histopathologic features and disease progression.(#br)Methods(#br)Institutional review board approval for this retrosp...
作者:Rupal S. Bhatt , Ann M. Dvorak ...
来源:[J].The American Journal of Pathology(IF 4.522), 2017, Vol.187 (10), pp.2337-2347Elsevier
摘要:Tumors induce their heterogeneous vasculature by secreting vascular endothelial growth factor (VEGF)-A. Anti-VEGF/VEGF receptor (VEGFR) drugs treat cancer, but the underlying mechanisms remain unclear. An adenovirus expressing VEGF-A (Ad-VEGF-A 164 ) replicates the tumor vasculat...
作者:... Angela Coxon , Jon Oliner , Rupal S. Bhatt
来源:[J].Translational Oncology(IF 3.393), 2014, Vol.7 (2), pp.188-195Elsevier
摘要:Abstract(#br)Angiopoietin 2 (Ang2) is a secreted glycoprotein upregulated at sites of angiogenesis and has been implicated in cancer neovascularization. Recent studies have suggested efficacy of combined Ang and vascular endothelial growth factor receptor (VEGFR) inhibition for p...
作者:Rupal S. Bhatt , Samuel D. Kaffenberger ...
来源:[J].European Journal of Cancer(IF 5.061), 2016, Vol.52, pp.155-162Elsevier
摘要:Abstract(#br)Background(#br)A growing body of evidence has demonstrated the anti-neoplastic activity of statins. The objective of this study was to investigate the effect of statin use on survival in patients with metastatic renal cell carcinoma (mRCC) treated in the modern ...

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