全部文献期刊会议图书|学者科研项目
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作者:Erin Rothwell , Erin Johnson ...
来源:[J].Journal of Genetic Counseling(IF 1.454), 2017, Vol.26 (4), pp.690-696
摘要:The offering and acceptance of expanded carrier screening is increasing among pregnant women including women without an increased risk based on race, ethnicity or family history. The chances of a positive screening test have been reported to be as high as 24 % when multiple ...
作者:Jeanette Rothwell , Sarah Benafif ...
来源:[J].Familial Cancer(IF 1.935), 2017, Vol.16 (3), pp.433-440
摘要:In the United Kingdom, current screening guidelines for TP53 germline mutation carriers solely recommends annual breast MRI, despite the wide spectrum of malignancies typically seen in this group. This study sought to investigate the role of one-off non-contrast whole-body M...
作者:Dominic G. Rothwell , Manon Pillai ...
来源:[J].Cancer Immunology, Immunotherapy(IF 3.637), 2017, Vol.66 (11), pp.1425-1436
摘要:The primary aim of this clinical trial was to determine the feasibility of delivering first-generation CAR T cell therapy to patients with advanced, CEACAM5+ malignancy. Secondary aims were to assess clinical efficacy, immune effector function and optimal dose of ...
作者:... Martin G. Evans , Simon M. Hutchinson , James J. Rothwell
来源:[J].Journal of Soils and Sediments(IF 1.965), 2017, Vol.17 (11), pp.2637-2647
摘要:Despite substantial research into Pb storage in peatlands, formal description of the mechanisms of contaminated sediment mobilisation is limited. This study explores the controlling factors of contaminated sediment dynamics in an eroding peatland in the Peak District National Par...
作者:Rachel R Hurley , James J Rothwell , Jamie C Woodward
来源:[J].Journal of Soils and Sediments(IF 1.965), 2017, Vol.17 (11), pp.2648-2665
摘要:Manchester is often heralded as the first industrial city. Large volumes of physical and liquid contaminants were released into its river network throughout the industrial period up to the latter part of the twentieth century. Water quality has improved dramatically in recent dec...
作者:Nancy J. Rothwell , Cay M. Kielty ...
来源:[J].Stem Cell Research & Therapy(IF 3.652), 2017, Vol.8 (1)
摘要:Inflammation is a key contributor to central nervous system (CNS) injury such as stroke, and is a major target for therapeutic intervention. Effective treatments for CNS injuries are limited and applicable to only a minority of patients. Stem cell-based therapies are increasingly...
作者:Joanne C. Rothwell , Craig R. Ramsay ...
来源:[J].Trials(IF 2.206), 2017, Vol.18 (1)
摘要:A key step in the design of a randomised controlled trial (RCT) is the estimation of the number of participants needed. By far the most common approach is to specify a target difference and then estimate the corresponding sample size; this sample size is chosen to provide reassur...
作者:Lincoln Rothwell , Daniel Oertli
来源:[J].Trials(IF 2.206), 2017, Vol.18 (1)
摘要:Laparoscopic Roux-en-Y gastric bypass (LRYGB) is considered the gold standard in bariatric surgery, achieving durable long-term weight loss with improvement of obesity-related comorbidities. Lately, the laparoscopic mini gastric bypass (LMGB) has gained worldwide popularity with ...
作者:Erin Rothwell , Bob Wong ...
来源:[J].Journal of Community Genetics, 2017, Vol.8 (3), pp.239-241
摘要:The purpose of this research was to assess the impact of an educational intervention on paternal knowledge, attitudes, and support about newborn screening (NBS) and dried blood spots (DBS). Participants ( n = 147) were randomized into one of two groups. The results from this stud...

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