全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Romany L. Stansborough , Emma H. Bateman ...
来源:[J].Supportive Care in Cancer(IF 2.649), 2017, Vol.25 (6), pp.1973-1983Springer
摘要:Radiotherapy-induced gut toxicity (RIGT) is associated with diarrhoea, pain and rectal bleeding and can occur as an acute or chronic toxicity. The microvasculature has been shown to be altered in the development of RIGT; however, the features are not yet characterized. We hypothe...
作者:Romany L. Stansborough , Noor Al-Dasooqi ...
来源:[J].Supportive Care in Cancer(IF 2.649), 2018, Vol.26 (11), pp.3873-3882Springer
摘要:Abstract(#br) Purpose(#br)Radiotherapy-induced gut toxicity (RIGT) is associated with significant diarrhoea, pain and rectal bleeding. Matrix metalloproteinases (MMPs) have been reported to be involved in chemotherapy-induced gut toxicity and RIGT following single-dose irrad...
作者:Romany L. Stansborough , Zenab Lightwala ...
来源:[J].Cancer Chemotherapy and Pharmacology(IF 2.795), 2017, Vol.79 (2), pp.431-434Springer
摘要:Abstract(#br) Purpose(#br)Irinotecan-induced gut toxicity is mediated in part by Toll-Like receptor 4 (TLR4) signalling. The primary purpose of this preclinical study was to determine whether blocking TLR4 signalling by administering (−)-naloxone, a TLR4 antagonist, would im...
作者:Romany L. Stansborough , Emma H. Bateman ...
来源:[J].International Journal of Radiation Biology(IF 1.895), 2018, Vol.94 (7), pp.645-655Taylor & Francis
摘要:Abstract(#br)Purpose:(#br) Radiotherapy-induced gut toxicity (RIGT) is a debilitating effect of radiotherapy for cancer, often resulting in significant diarrhea and pain. Previous studies have highlighted roles of the intestinal microvasculature and matrix metalloproteinases...
作者:Romany L. Stansborough , Noor Al-dasooqi ...
来源:[J].International Journal of Radiation Biology(IF 1.895), 2016, Vol.92 (5), pp.241-248Taylor & Francis
摘要:Abstract(#br)Purpose(#br) To review the literature surrounding the involvement of the endothelium and matrix metalloproteinases (MMP) in radiotherapy-induced gut toxicity (RIGT) and further elucidate its complex pathobiology.(#br)Results(#br) RIGT involves damage to the gastroint...
作者:Romany L. Stansborough , Rachel J. Gibson
来源:[J].Current Opinion in Supportive and Palliative Care, 2017Wolters Kluwer
摘要:PURPOSE OF REVIEW: Gastrointestinal toxicities are commonly reported following treatment with proteasome inhibitors. The first-generation proteasome inhibitor, bortezomib, induces significant gastrointestinal side effects including nausea, vomiting, diarrhoea, and constipation, o...

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