全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:... Teow Chong Teoh , Noorsaadah A. Rahman , Rohana Yusof
来源:[J].International Journal of Peptide Research and Therapeutics(IF 1.28), 2017, Vol.23 (2), pp.163-170Springer
摘要:The emerging of hepatitis C virus (HCV) resistant strains has been considered as a main drawback of the available drugs. Since HCV has a large inactive surface, we would like to hypothesis that the mutation occur in HCV is minimal and causing less resistance against inhibiti...
作者:... Zi Ling Yong , Rohana Yusof , Roger J. Watson
来源:[J].Virology Journal(IF 2.092), 2016, Vol.13 (1)Springer
摘要:Abstract(#br) Background(#br)Retinoblastoma like protein 2 (RBL2) or p130 is a member of the pocket protein family, which is infrequently mutated in human tumours. Its expression is posttranscriptionally regulated and largely G0 restricted. We have previously shown that E6/E7 onc...
作者:... Zulqarnain Mohamed , Noorsaadah Abd Rahman , Rohana Yusof
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.9 (4)DOAJ
摘要:Dengue virus (DENV) broadly disseminates in tropical and sub-tropical countries and there are no vaccine or anti-dengue drugs available. DENV outbreaks cause serious economic burden due to infection complications that requires special medical care and hospitalization. This s...
作者:Rohana Yusof , Puteri Shafinaz Akmar Abdul-Rahman
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.8 (4)DOAJ
摘要:BACKGROUND: Chikungunya virus (CHIKV) is an emerging mosquito-borne alphavirus that has caused multiple unprecedented and re-emerging outbreaks in both tropical and temperate countries. Despite ongoing research efforts, the underlying factors involved in facilitating CHIKV replic...
作者:... Teow Chong Teoh , Hussin A. Rothan , Rohana Yusof
来源:[J].International Journal of Peptide Research and Therapeutics(IF 1.28), 2019, Vol.25 (4), pp.1659-1668Springer
摘要:Abstract(#br)Zika virus (ZIKV) is a Flavivirus associated with several neurological complications. Currently, there are no vaccines or cures available and an efficient antiviral treatment is urgently needed to combat ZIKV infection. Herein, we targeted ZIKV NS2B-NS3 serine p...
作者:... Shatrah Othman , Noorsaadah Abd Rahman , Rohana Yusof
来源:[J].Journal of Biomedicine and Biotechnology(IF 2.88), 2012, Vol.2012DOAJ
摘要:Dengue diseases have an economic as well as social burden worldwide. In this study, the antiviral activity of protegrin-1 (PG-1, RGGRLCYCRRRFCVCVGR) peptide towards dengue NS2B-NS3pro and viral replication in Rhesus monkey kidney (MK2) cells was investigated. The peptide PG-...
作者:... Ketha Amarnadh Reddy , Noorsaadah Abd Rahman , Rohana Yusof
来源:[J].International Journal of Peptide Research and Therapeutics(IF 1.28), 2014, Vol.20 (3), pp.259-267Springer
摘要:Abstract(#br)Even with the great advances in cancer therapies, cancer remains the major cause of death worldwide. The use of high doses of anti-cancer chemotherapeutic drugs eventually causes the inevitable damage in non-neoplastic cells. New, selective, and more effective drugs ...
作者:Rohana Yusof , Jun Hang ...
来源:[J].Antiviral Research(IF 3.925), 2019, Vol.171Elsevier
摘要:Abstract(#br)Two major flaviviruses, dengue virus (DENV) and Zika virus (ZIKV), cause severe health and economic burdens worldwide. Recently, genome-wide screenings have uncovered the importance of regulators of the Hrd1 ubiquitin ligase-mediated endoplasmic reticulum (ER)-associ...

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