全部文献期刊会议图书|学者科研项目
中外文文献  中文文献  外文文献
作者:Roger Perkins , Weigong Ge ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.7 (9)
摘要:During the last several years, high-density genotyping SNP arrays have facilitated genome-wide association studies (GWAS) that successfully identified common genetic variants associated with a variety of phenotypes. However, each of the identified genetic variants only explains a...
作者:Roger Perkins , Weida Tong
来源:[J].International Journal of Environmental Research and Public Health(IF 1.998), 2016, Vol.13 (4)
摘要:Flavonoids are frequently used as dietary supplements in the absence of research evidence regarding health benefits or toxicity. Furthermore, ingested doses could far exceed those received from diet in the course of normal living. Some flavonoids exhibit binding to estrogen ...
作者:Roger Perkins , Zhichao Liu ...
来源:[J].BMC Bioinformatics(IF 3.024), 2015, Vol.16 (13)
摘要:Abstract(#br) Background(#br)Topic modelling is an active research field in machine learning. While mainly used to build models from unstructured textual data, it offers an effective means of data mining where samples represent documents, and different biological endpoints or omi...
作者:Roger Perkins , Yuping Wang ...
来源:[J].BMC Bioinformatics(IF 3.024), 2016, Vol.17 (1)
摘要:Abstract(#br) Background(#br)Next-generation sequencing (NGS) technologies have provided researchers with vast possibilities in various biological and biomedical research areas. Efficient data mining strategies are in high demand for large scale comparative and evolutional studie...
作者:Roger Perkins , Leming Shi
来源:[J].Analytical Biochemistry(IF 2.582), 2008, Vol.385 (2), pp.203-207
摘要:Abstract(#br)Quality control of a microarray experiment has become an important issue for both research and regulation. External RNA controls (ERCs), which can be either added to the total RNA level (tERCs) or introduced right before hybridization (cERCs), are designed and r...
作者:Roger Perkins , Xueguang Shao ...
来源:[J].Computational Biology and Chemistry(IF 1.793), 2007, Vol.31 (1), pp.48-56
摘要:Abstract(#br)Class prediction based on DNA microarray data has been emerged as one of the most important application of bioinformatics for diagnostics/prognostics. Robust classifiers are needed that use most biologically relevant genes embedded in the data. A consensus approach t...
作者:Roger Perkins , Weida Tong
来源:[J].International Journal of Environmental Research and Public Health(IF 1.998), 2014, Vol.11 (9), pp.8709-8742
摘要:The estrogen receptors (ERs) are a group of versatile receptors. They regulate an enormity of processes starting in early life and continuing through sexual reproduction, development, and end of life. This review provides a background and structural perspective for the ERs as par...
作者:Roger Perkins , Hong Fang ...
来源:[J].Journal of Genetics(IF 0.876), 2010, Vol.89 (1), pp.55-64
摘要:Abstract(#br)Genome-wide association studies (GWAS) examine the entire human genome with the goal of identifying genetic variants (usually single nucleotide polymorphisms (SNPs)) that are associated with phenotypic traits such as disease status and drug response. The discordance ...

我们正在为您处理中,这可能需要一些时间,请稍等。

资源合作:cnki.scholar@cnki.net, +86-10-82896619   意见反馈:scholar@cnki.net

×