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作者:Rodrigo Fernandez-Valdivia , John P Lydon ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.11 (7)
摘要:Ovarian steroids, estradiol and progesterone, play central roles in regulating female reproduction by acting as both positive and negative regulators of gonadotropin-releasing hormone (GnRH) secretion in the hypothalamus. Recent studies have identified kisspeptin neurons of the h...
作者:Rodrigo Fernandez-Valdivia , John P. Lydon
来源:[J].Molecular and Cellular Endocrinology(IF 4.039), 2012, Vol.357 (1-2), pp.91-100
摘要:Abstract(#br)Whether during the diestrus phase of the estrous cycle or with pregnancy onset, the mitogenic effects of progesterone are well-established in the murine mammary epithelium. Importantly, progesterone-induced mitogenicity is critical for mammary tumor promotion, p...
作者:Rodrigo Fernandez-Valdivia , Atish Mukherjee ...
来源:[J].Developmental Biology(IF 3.868), 2009, Vol.328 (1), pp.127-139
摘要:Abstract(#br)Receptor of Activated NF-κB Ligand (RANKL) is implicated as one of a number of effector molecules that mediate progesterone and prolactin signaling in the murine mammary epithelium. Using a mouse transgenic approach, we demonstrate that installation of the RANKL...
作者:... Michael Ittmann , Rodrigo Fernandez-Valdivia , John P. Lydon
来源:[J].Cytokine(IF 2.518), 2019, Vol.123
摘要:Abstract(#br)Although salivary gland cancers comprise only ∼3–6% of head and neck cancers, treatment options for patients with advanced-stage disease are limited. Because of their rarity, salivary gland malignancies are understudied compared to other exocrine tissue cancers....
作者:Rodrigo Fernandez-Valdivia , Jonathan Nguyen ...
来源:[J].Journal of Steroid Biochemistry and Molecular Biology(IF 3.984), 2006, Vol.102 (1), pp.22-31
摘要:Abstract(#br)While the indispensability of the progesterone receptor (PR) in female reproduction and mammary morphogenesis is acknowledged, the coregulators preferentially recruited by PR to mediate its in vivo effects have yet to be fully delineated. To further parse the roles o...
作者:Rodrigo Fernandez-Valdivia , John P. Lydon ...
来源:[J].PLOS ONE(IF 3.73), 2016, Vol.11 (7)
摘要:Ovarian steroids, estradiol and progesterone, play central roles in regulating female reproduction by acting as both positive and negative regulators of gonadotropin-releasing hormone (GnRH) secretion in the hypothalamus. Recent studies have identified kisspeptin neurons of the h...
作者:Rodrigo Fernandez-Valdivia , Atish Mukherjee ...
来源:[J].Semin Reprod Med(IF 3.211), 2005, Vol.23 (1), pp.22-37
摘要:Apart from distinguishing the in vivo effects of progesterone (P) from those of estrogen (E), the progesterone receptor knockout (PRKO) mouse has furnished unprecedented access to novel cell-signaling paradigms, hitherto unsuspected. Along with providing new cellular principles b...

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