全部文献期刊会议图书|学者科研项目
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作者:Roberto Vera , Gabriel Padron
来源:[J].Journal of Proteomics(IF 4.088), 2011, Vol.74 (10), pp.2071-2082
摘要:Abstract(#br)Protein identification by mass spectrometry is mainly based on MS/MS spectra and the accuracy of molecular mass determination. However, the high complexity and dynamic ranges for any species of proteomic samples, surpass the separation capacity and detection pow...
作者:Roberto Vera , Yuliet Mazola
来源:[J].Current Topics in Medicinal Chemistry(IF 3.702), 2012, Vol.12 (16), pp.1790-1796
摘要:Computational algorithms to explore the conformational space of small molecules are complex and computerdemand field in chemoinformatics. In this paper a hybrid algorithm to explore the conformational space of organic moleculesis presented. This hybrid algorithm is based in a sys...
作者:Roberto Vera , Balázs Győrffy
来源:[J].PLOS ONE(IF 3.73), 2015, Vol.10 (6)
摘要:Drug combinations are highly efficient in systemic treatment of complex multigene diseases such as cancer, diabetes, arthritis and hypertension. Most currently used combinations were found in empirical ways, which limits the speed of discovery for new and more effective combinati...
作者:Lőrinc S. Pongor , Roberto Vera , Balázs Ligeti
来源:[J].PLOS ONE(IF 3.73), 2014, Vol.9 (7)
摘要:Next generation sequencing (NGS) of metagenomic samples is becoming a standard approach to detect individual species or pathogenic strains of microorganisms. Computer programs used in the NGS community have to balance between speed and sensitivity and as a result, species or stra...
作者:Roberto Vera , Sándor Pongor
来源:[J].PLOS ONE(IF 3.73), 2014, Vol.9 (5)
摘要:The comQXPA locus of Bacillus subtilis encodes a quorum sensing (QS) system typical of Gram positive bacteria. It encodes four proteins, the ComQ isoprenyl transferase, the ComX pre-peptide signal, the ComP histidine kinase, and the ComA response regulator. These are encoded by f...
作者:Roberto Vera , Michael P. Myers ...
来源:[J].Bioinformatics(IF 5.323), 2014, Vol.30 (2), pp.234-241
摘要:Motivation: Tandem mass spectrometry has become a standard tool for identifying post-translational modifications (PTMs) of proteins. Algorithmic searches for PTMs from tandem mass spectrum data (MS/MS) tend to be hampered by noisy data as well as by a combinatorial explosion of s...

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