全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Ramasamy Kesavan , Jayaraman Balachandar
来源:[J].Pharmacological Reports(IF 1.965), 2015, Vol.67 (1), pp.97-101Elsevier
摘要:Abstract(#br)Background(#br)Cardiovascular diseases (CVDs) are the major cause of mortality and morbidity worldwide. Myocardial infarction (MI) is a complex multi-factorial, polygenic disorder arising from an interaction between genetic makeup of individuals and various envi...
作者:Ramasamy Kesavan , Narayan Sunil ...
来源:[J].Neurology India(IF 1.044), 2007, Vol.55 (4), pp.408DOAJ
摘要:The authors report an Indian adult female patient with a history of generalized tonic clonic seizures who developed severe features of phenytoin (DPH) toxicity on therapeutic dosage of this antiepileptic drug. Administration of 300mg/day of DPH in this patient resulted in to...
作者:Ramasamy Kesavan , Sunil K. Narayan , Chandrasekaran Adithan
来源:[J].European Journal of Clinical Pharmacology(IF 2.741), 2010, Vol.66 (7), pp.689-696Springer
摘要:Abstract(#br) Objective(#br)Cytochrome P450 2C9 and 2C19 ( CYP2C9 and CYP2C19 , respectively) genetic polymorphisms play an important role in phenytoin (PHT) metabolism. We have evaluated whether these genetic polymorphisms have an effect on PHT-induced neurological toxicity...
作者:Ramasamy Kesavan , Sisy Sam Soya , Chandrasekaran Adithan
来源:[J].Drug metabolism and pharmacokinetics(IF 2.071), 2006, Vol.21 (6), pp.506-8PubMed
摘要:The allele and genotype frequencies of MDR1 C3435T polymorphism were determined in 185 unrelated healthy Tamilians. The genomic DNA was extracted from peripheral leucocytes using phenol chloroform method and genotyped by PCR-RFLP method. The frequencies of MDR1 C3435 and T3435 al...

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