全部文献期刊会议图书|学者科研项目
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作者:Ram Vinay Pandey , Christian Schlötterer
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.8 (8)
摘要:With the rapid and steady increase of next generation sequencing data output, the mapping of short reads has become a major data analysis bottleneck. On a single computer, it can take several days to map the vast quantity of reads produced from a single Illumina HiSeq lane. In an...
作者:Ram Vinay Pandey , Stephan Pabinger ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.11 (2)
摘要:Traditional Sanger sequencing as well as Next-Generation Sequencing have been used for the identification of disease causing mutations in human molecular research. The majority of currently available tools are developed for research and explorative purposes and often do not provi...
作者:Ram Vinay Pandey , Barbara Blasi
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.9 (10)
摘要:The draft genome of the Antarctic endemic fungus Cryomyces antarcticus is presented. This rock inhabiting, microcolonial fungus is extremely stress tolerant and it is a model organism for exobiology and studies on stress resistance in Eukaryots. Since this fungus is a specialist ...
作者:Ram Vinay Pandey , Susanne U Franssen ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.8 (12)
摘要:It is generally accepted that gene regulation serves an important role in determining the phenotype. To shed light on the evolutionary forces operating on gene regulation, previous studies mainly focused on the expression differences between species and their inter-specific hybri...
作者:Ram Vinay Pandey , Stephan Pabinger ...
来源:[J].BMC Bioinformatics(IF 3.024), 2016, Vol.17 (1)
摘要:Abstract(#br) Background(#br)Traditional Sanger sequencing has been used as a gold standard method for genetic testing in clinic to perform single gene test, which has been a cumbersome and expensive method to test several genes in heterogeneous disease such as cancer. With the a...
作者:... Akriti Kashyap , Ram Vinay Pandey , Kulvinder Singh Saini
来源:[J].Drug Discovery Today(IF 6.551), 2011, Vol.16 (17), pp.793-799
摘要:The cytochrome P450 (CYP) enzymes, involved in the metabolism of therapeutic drugs, are the major determinants of drug half-life. From a drug industry perspective, variability in drug response owing to CYP polymorphisms makes CYP profiling a commercially interesting option for di...
作者:Ram Vinay Pandey , Robert Kofler ...
来源:[J].BMC Genetics(IF 2.808), 2011, Vol.12 (1)
摘要:Abstract(#br) Background(#br)The enormous potential of natural variation for the functional characterization of genes has been neglected for a long time. Only since recently, functional geneticists are starting to account for natural variation in their analyses. With the new...

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