全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:... Sivanantham Ayyanar , Rajaguru Palanichamy , Rajasekaran Subbiah
来源:[J].Pharmacological Reports(IF 1.965), 2016Elsevier
摘要:Abstract(#br)Background(#br)Epithelial mesenchymal transition (EMT) is a process through which epithelial cells undergo multiple biochemical changes, causing them to differentiate into a mesenchymal-cell phenotype. This process has been shown to contribute to the development...
作者:... Ayyanar Sivanantham , Rajaguru Palanichamy , Subbiah Rajasekaran
来源:[J].Pharmacological Reports(IF 1.965), 2017, Vol.69 (3), pp.426-431Springer
摘要:Abstract(#br)Background(#br)Epithelial mesenchymal transition (EMT) is a process through which epithelial cells undergo multiple biochemical changes, causing them to differentiate into a mesenchymal-cell phenotype. This process has been shown to contribute to the development...
作者:Rajaguru Palanichamy , Karthikeyan Muthusamy
来源:[J].Inflammation Research(IF 1.964), 2019, Vol.68 (12), pp.1011-1024Springer
摘要:Abstract(#br) Background(#br)Polarized macrophages induce fibrosis through multiple mechanisms, including a process termed epithelial-to-mesenchymal transition (EMT). Mesenchymal cells contribute to the excessive accumulation of fibrous connective tissues, leading to organ failur...
作者:... Vignesh Thiagarajan , Rajaguru Palanichamy , Ruckmani Kandasamy
来源:[J].International Journal of Biological Macromolecules(IF 2.596), 2017Elsevier
摘要:Abstract(#br)Clinical use of camptothecin (CPT) is hindered due to its poor water and oil solubility, active lactone ring instability and non-targeted toxicity. Recently we reported formulation of camptothecin microemulsions with increased solubility for the improved treatme...
作者:... Senthilkumar Chelladurai , Sharavanan Shanmugam Palaniappan , Rajaguru Palanichamy
来源:[J].International Journal of Biological Macromolecules(IF 2.596), 2017Elsevier
摘要:Abstract(#br)Artemisinin, a natural anti-malarial agent, also possesses anti-proliferative and anti-angiogenic activity in cancer cells with very low toxicity to normal healthy cells. Drug loaded magnetic nanoparticlesby using external magnetic field could selectively accumu...
作者:Rajaguru Palanichamy , Sivakumar Muthusamy
来源:[J].International Journal of Biological Macromolecules(IF 2.596), 2017Elsevier
摘要:Abstract(#br)Natural anti-oxidants resveratrol (RES) and quercetin (QUR) posses the ability to reduce intra ocular pressure efficiently. Concurrent administration of RES and QUR was able to enhance the bioavailability of RES. Present research work describes upsurge of QUR in...
作者:Rajaguru Palanichamy , Ruckmani Kandasamy ...
来源:[J].European Journal of Pharmaceutical Sciences(IF 2.987), 2018, Vol.116, pp.15-25Elsevier
摘要:Abstract(#br)Targeted delivery of anticancer agents is poised to improve cancer therapy, for which polymers can serve as targeting ligands or nanocarriers for chemotherapeutic agents. In this study, we have developed and evaluated the efficacy of a camptothecin (CPT)-loaded ...
作者:Rajaguru Palanichamy , Ruckmani Kandasamy
来源:[J].European Journal of Pharmaceutical Sciences(IF 2.987), 2018, Vol.116, pp.26-36Elsevier
摘要:Abstract(#br)In the present work, we have developed a photosensitizer hypocrellin B (HB) and nano silver loaded PLGA-TPGS nanoparticles with improved singlet oxygen production for enhanced photodynamic effect for the efficient treatment of age related macular degeneration. R...
作者:... Ruckmani Kandasamy , Subramanian Natesan , Rajaguru Palanichamy
来源:[J].International Journal of Biological Macromolecules(IF 2.596), 2018, Vol.110, pp.336-345Elsevier
摘要:Abstract(#br)This research was aimed to develop and evaluate nepafenac loaded silica nanoparticles dispersed in-situ gel system for the improved treatment of ocular diseases. The blank silica nanoparticles prepared by stober’s process showed the particle size of 151 nm to 28...
作者:... Vinoth Jeevanesan , Gangarani Girija , Rajaguru Palanichamy
来源:[J].Journal of Drug Targeting(IF 2.768), 2014, Vol.22 (10), pp.913-926Informa Healthcare
摘要:Abstract Purpose : Development and evaluation of camptothecin-loaded-microemulsion (ME) and -magnetic microemulsion (MME) for passive/active-targeted delivery to BALB/c mice-bearing breast cancer. Methods : Based on the pseudo-ternary phase diagrams camptothecin-loaded-MEs and -M...

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