全部文献期刊会议图书|学者科研项目
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作者:Qirong Wen , Qi Yin ...
来源:[J].Journal of Experimental & Clinical Cancer Research(IF 3.066), 2017, Vol.36 (1)
摘要:Ovarian carcinoma is one of the most aggressive gynecological malignant neoplasms and makes up 25–30% of all cancer cases of the female genital tract. Currently, resistance to traditional chemotherapy is a great challenge for patients with Epithelial ovarian cancer (EOC). Th...
作者:Qirong Wen , Jiao Liu ...
来源:[J].Biochemical and Biophysical Research Communications(IF 2.406), 2019, Vol.510 (2), pp.278-283
摘要:Abstract(#br)Damage-associated molecular pattern molecules (DAMPs) are endogenous danger signals that alert the innate immune system and shape the inflammation response to cell death. However, the release and activity of DAMPs in ferroptosis, a recently identified form of re...
作者:Qirong Wen , Juan Li ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.11 (5)
摘要:Metastasis associated in lung adenocarcinoma transcript-1 (MALAT-1) is overexpressed during cancer progression and promotes cell migration and invasion in many solid tumors. However, its role in ovarian cancer remains poorly understood.Expressions of MALAT-1 were detected in 37 n...
作者:Qirong Wen , Yuhuan Xie ...
来源:[J].BioMed Research International, 2019, Vol.2019
摘要:To explore the antitumor effect of hypoxia-inducible factor-1 α short hairpin RNA (HIF-1 α shRNA) delivered by ultrasound targeted microbubble destruction (UTMD) and transcatheter arterial embolization (TAE) on rats with hepatic cancer. After the models of transplantation he...
作者:Qirong Wen , Lizhi Cao ...
来源:[J].Cell Host & Microbe(IF 12.609), 2018, Vol.24 (1), pp.97-108.e4
摘要:Summary(#br)Sepsis is a life-threatening condition caused by pathogen infection and associated with pyroptosis. Pyroptosis occurs upon activation of proinflammatory caspases and their subsequent cleavage of gasdermin D (GSDMD), resulting in GSDMD N-terminal fragments that fo...
作者:Qirong Wen , Jiao Liu ...
来源:[J].Current Biology(IF 9.494), 2018
摘要:Summary(#br)Ferroptosis is a form of regulated cell death triggered by lipid peroxidation after inhibition of the cystine/glutamate antiporter system X c – . However, key regulators of system X c – activity in ferroptosis remain undefined. Here, we show that BECN1 plays a hi...
作者:Qirong Wen , Yangchun Xie ...
来源:[J].Developmental Cell(IF 12.861), 2018
摘要:Summary(#br)Pancreatic cancer is an aggressive malignancy with changes in the tumor microenvironment. Here, we demonstrate that PINK1 and PARK2 suppressed pancreatic tumorigenesis through control of mitochondrial iron-dependent immunometabolism. Using mouse models of spontan...
作者:Qirong Wen , Yan Liu ...
来源:[J].International Journal of Gynecological Cancer(IF 1.941), 2017
摘要:OBJECTIVES: The aims of this study were to investigate the functions of GAS5 as a tumor suppressor in cervical cancer and explore the mechanism. METHODS: The expression of GAS5 and microRNA 21 (miR-21) was detected in primary cervical cancer tissue specimens, as well as in cervic...
作者:Qirong Wen , Juan Li ...
来源:[J].PLOS ONE(IF 3.73), 2016, Vol.11 (5)
摘要:Metastasis associated in lung adenocarcinoma transcript-1 (MALAT-1) is overexpressed during cancer progression and promotes cell migration and invasion in many solid tumors. However, its role in ovarian cancer remains poorly understood.;;Expressions of MALAT-1 were detected in 37...

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