全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Qifan Kuang , Zhining Wen ...
来源:[J].BMC Genomics(IF 4.397), 2017, Vol.18 (1)Springer
摘要:TEs pervade mammalian genomes. However, compared with mice, fewer studies have focused on the TE expression patterns in rat, particularly the comparisons across different organs, developmental stages and sexes. In addition, TEs can influence the expression of nearby genes. The te...
作者:Qifan Kuang , Zhining Wen
来源:[J].BMC Bioinformatics(IF 3.024), 2017, Vol.18 (14)Springer
摘要:Endometrial cancers (ECs) are one of the most common types of malignant tumor in females. Substantial efforts had been made to identify significantly mutated genes (SMGs) in ECs and use them as biomarkers for the classification of histological subtypes and the prediction of clini...
作者:Qifan Kuang , Daichuan Ma ...
来源:[J].Chemometrics and Intelligent Laboratory Systems(IF 2.291), 2018, Vol.172, pp.241-247Elsevier
摘要:Abstract(#br)Biomarker discovery plays an important role in cancer diagnosis and prognosis assessments. The biomarkers that could be applied among different cancer types are highly useful. Although many traditional feature selection algorithms have shown their power on picki...
作者:Qifan Kuang , Yizhou Li ...
来源:[J].Chemometrics and Intelligent Laboratory Systems(IF 2.291), 2017, Vol.162, pp.104-110Elsevier
摘要:Abstract(#br)The prediction of drug-target interactions plays an important role in the drug discovery process, which serves to identify new drugs or novel targets for existing drugs. However, experimental methods for predicting drug-target interactions are expensive and time-cons...
作者:Qifan Kuang , Juan Zhang ...
来源:[J].Computational Biology and Chemistry(IF 1.793), 2014, Vol.49, pp.71-78Elsevier
摘要:Abstract(#br)Estrogen receptor status and the pathologic response to preoperative chemotherapy are two important indicators of chemotherapeutic sensitivity of tumors in breast cancer, which are used to guide the selection of specific regimens for patients. Microarray-based gene e...
作者:Qifan Kuang , Yiming Wu ...
来源:[J].Chemometrics and Intelligent Laboratory Systems(IF 2.291), 2015, Vol.144, pp.71-79Elsevier
摘要:Abstract(#br)Correctly and efficiently identifying associations between drugs and adverse drug reactions (ADRs) is critically important for drug development and clinical safety. Because of their low costs and high performance, many statistical and machine learning methods ha...
作者:Qifan Kuang , Yongcheng Dong ...
来源:[J].Chemometrics and Intelligent Laboratory Systems(IF 2.291), 2016, Vol.156, pp.224-230Elsevier
摘要:Abstract(#br)Benefiting from the high-throughput sequencing technologies, many single nucleotide variants (SNVs) among individuals have been detected. SNVs in gene code regions were known to possibly disrupt protein functions. For this, many efforts were devoted to sort dele...
作者:Qifan Kuang , Lin Jiang ...
来源:[J].Chemometrics and Intelligent Laboratory Systems(IF 2.291), 2014, Vol.131, pp.16-21Elsevier
摘要:Abstract(#br)Hot spots residues in protein–protein interface play crucial roles in protein binding. In the present study, complex network method was applied to uncover influence of neighboring residues on hot spots and then several network and microenvironment features were ...
作者:Qifan Kuang , Ling Ye ...
来源:[J].Amino Acids(IF 3.914), 2014, Vol.46 (8), pp.2025-2035Springer
摘要:Abstract(#br)Single-nucleotide polymorphisms (SNPs) are the most frequent form of genetic variations. Non-synonymous SNPs (nsSNPs) occurring in coding region result in single amino acid substitutions that associate with human hereditary diseases. Plenty of approaches were de...
作者:Qifan Kuang , Xuemei Pu ...
来源:[J].Journal of Computer-Aided Molecular Design(IF 3.172), 2015, Vol.29 (4), pp.349-360Springer
摘要:Abstract(#br)The assessment of binding affinity between ligands and the target proteins plays an essential role in drug discovery and design process. As an alternative to widely used scoring approaches, machine learning methods have also been proposed for fast prediction of ...

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