全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Ying Li , Luo Liu , Pingfang Tian
来源:[J].Biotechnology Letters(IF 1.853), 2014, Vol.36 (11), pp.2215-2221Springer
摘要:Abstract(#br)The limiting step for biosynthesis of 3-hydroxypropionic acid (3-HP) in Klebsiella pneumoniae is the conversion of 3-hydroxypropionaldehyde (3-HPA) to 3-HP. This reaction is catalyzed by aldehyde dehydrogenase (ALDH) with NAD + as a cofactor. Although NAD + -dep...
作者:... Ying Li , Xizhen Ge , Pingfang Tian
来源:[J].Biotechnology Letters(IF 1.853), 2015, Vol.37 (3), pp.717-724Springer
摘要:Abstract(#br)In Klebsiella pneumoniae , aldehyde dehydrogenases (ALDH) convert 3-hydroxypropionaldehyde (3-HPA) into 3-hydroxypropionic acid (3-HP). Although ALDHs can increase the production of 3-HP in K. pneumoniae , the substrate specificity of ALDH homologues from other ...
作者:Kang Wang , Pingfang Tian
来源:[J].Current Microbiology(IF 1.52), 2017, Vol.74 (1), pp.55-58Springer
摘要:Abstract(#br)Although plasmid-dependent microbial breeding is predominant in manufacturing bio-based chemicals, it shows pitfall of genetic instability and thus hinders industrial production. Alternatively, chromosome engineering free from plasmid enables genetic stability and th...
作者:... Mingyue Su , Xizhen Ge , Pingfang Tian
来源:[J].Biotechnology Letters(IF 1.853), 2013, Vol.35 (10), pp.1609-1615Springer
摘要:Abstract(#br)In Klebsiella pneumoniae , 3-hydroxypropaldehyde is converted to 3-hydroxypropionic acid (3-HP) by aldehyde dehydrogenase (ALDH) with NAD + as a cofactor. Although ALDH overexpression stimulates the formation of 3-HP, it ceases to accumulate when NAD + is exhausted. ...
作者:... Qinghui Pei , Xizhen Ge , Pingfang Tian
来源:[J].Crop Protection(IF 1.303), 2016Elsevier
摘要:Abstract(#br)Berberine (BBR) is a traditional antidiarrheal compound with excellent safety profiles. Our previous study reported that BBR strongly inhibited brown rot pathogen Monilinia fructicola . In this study we assess its potential commercial performance. We found that ...
作者:... Ying Li , Xizhen Ge , Pingfang Tian
来源:[J].Crop Protection(IF 1.303), 2019, Vol.116, pp.92-100Elsevier
摘要:Abstract(#br)The brown rot disease caused by fungus Monilinia fructicola severely reduces the yield of peach and other stone fruits. Earlier, we found that berberine (BBR), one of isoquinoline alkaloids, strongly halts the growth of M . fructicola . However, the underlying mechan...
作者:Liuni Chen , Ying Li , Pingfang Tian
来源:[J].Indian Journal of Microbiology(IF 0.457), 2016, Vol.56 (2), pp.190-197Springer
摘要:Abstract(#br)Plasmid-dependent overexpression of enzyme(s) aims to divert carbon flux toward a desired compound. One drawback of this strategy is compromise of growth due to massive consumption of host resources. Here we show that replenishment of sigma factor rpoE improves the g...
作者:... Zengye Han , Xizhen Ge , Pingfang Tian
来源:[J].Current Microbiology(IF 1.52), 2014, Vol.69 (4), pp.451-456Springer
摘要:Abstract(#br)Pyrroloquinoline quinone (PQQ) is a versatile quinone cofactor participating in numerous biological processes. Klebsiella pneumoniae can naturally synthesize PQQ for harboring intact PQQ synthesis genes. Previous metabolic engineering of K . pneumoniae failed to...
作者:Ying Li , Pingfang Tian
来源:[J].Indian Journal of Microbiology(IF 0.457), 2015, Vol.55 (2), pp.131-139Springer
摘要:Abstract(#br)3-Hydroxypropionic acid (3-HP) is a commercially valuable platform chemical from which an array of C3 compounds can be generated. Klebsiella pneumoniae has been considered a promising species for biological production of 3-HP. Despite a wealth of reports r...

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