全部文献期刊会议图书|学者科研项目
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作者:Phillip D. Fletcher , Camilla N. Clark ...
来源:[J].Journal of Neurology(IF 3.578), 2018, Vol.265 (6), pp.1474-1490Springer
摘要:Abstract(#br)The primary progressive aphasias are a heterogeneous group of focal ‘language-led’ dementias that pose substantial challenges for diagnosis and management. Here we present a clinical approach to the progressive aphasias, based on our experience of these disorder...
作者:Phillip D. Fletcher , Laura E. Downey ...
来源:[J].Cortex(IF 6.161), 2015, Vol.67, pp.95-105Elsevier
摘要:Abstract(#br)Patients with dementia may exhibit abnormally altered liking for environmental sounds and music but such altered auditory hedonic responses have not been studied systematically. Here we addressed this issue in a cohort of 73 patients representing major canonical...
作者:Phillip D. Fletcher , Jennifer M. Nicholas ...
来源:[J].Cortex(IF 6.161), 2016, Vol.77, pp.13-23Elsevier
摘要:Abstract(#br)The meaning of sensory objects is often behaviourally and biologically salient and decoding of semantic salience is potentially vulnerable in dementia. However, it remains unclear how sensory semantic processing is linked to physiological mechanisms for coding o...
作者:Phillip D. Fletcher , Catherine J. Mummery ...
来源:[J].Cortex(IF 6.161), 2015, Vol.69, pp.47-59Elsevier
摘要:Abstract(#br)Humour is a complex cognitive and emotional construct that is vulnerable in neurodegenerative diseases, notably the frontotemporal lobar degenerations. However, humour processing in these diseases has been little studied. Here we assessed humour processing in patient...
作者:Phillip D. Fletcher , Kankamol Jaisin ...
来源:[J].Neuropsychologia(IF 3.477), 2016, Vol.81, pp.245-254Elsevier
摘要:Abstract(#br)Abstract art may signal emotions independently of a biological or social carrier: it might therefore constitute a test case for defining brain mechanisms of generic emotion decoding and the impact of disease states on those mechanisms. This is potentially of particul...
作者:Phillip D. Fletcher , Laura E. Downey ...
来源:[J].Neuropsychologia(IF 3.477), 2013, Vol.51 (9), pp.1709-1715Elsevier
摘要:Abstract(#br)As an example of complex auditory signal processing, the analysis of accented speech is potentially vulnerable in the progressive aphasias. However, the brain basis of accent processing and the effects of neurodegenerative disease on this processing are not well unde...
作者:Phillip D. Fletcher , Pirada Witoonpanich ...
来源:[J].Journal of the Neurological Sciences(IF 2.243), 2014, Vol.347 (1-2), pp.345-348Elsevier
摘要:Abstract(#br)The pathophysiology of nonfluent primary progressive aphasia (nfvPPA) remains poorly understood. Here, we compared quantitatively speech parameters in patients with nfvPPA versus healthy older individuals under altered auditory feedback, which has been shown to modul...
作者:Phillip D. Fletcher , Jason D. Warren
来源:[J].Journal of Molecular Neuroscience(IF 2.891), 2011, Vol.45 (3)Springer
摘要:Abstract(#br)Semantic dementia (SD) is a unique syndrome in the frontotemporal lobar degeneration spectrum. Typically presenting as a progressive, fluent anomic aphasia, SD is the paradigmatic disorder of semantic memory with a characteristic anatomical profile of asymmetric, sel...

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