全部文献期刊会议图书|学者科研项目
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作者:Philippe Mathurin , François Durand ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.11 (3)DOAJ
摘要:No efficient medical treatment is available for severe acute hepatitis (SAH) except N-acetylcysteine for acetaminophen-induced acute liver failure. The human C-type lectin Reg3α, referred to as ALF-5755, improved survival in an animal model of acute liver failure and was wel...
作者:Philippe Mathurin , Lawrence Serfaty
来源:[J].PPAR Research(IF 2.685), 2009, Vol.2009DOAJ
摘要:The topic of peroxisome proliferator-activated receptors has been developed in the field of hepatology allowing envisaging therapeutic strategies for the most frequent chronic liver diseases such as chronic infection with hepatitis C virus (HCV). PPARs contribute to wide phy...
作者:... Antoine Hollebecque , Philippe Mathurin , Sébastien Dharancy
来源:[J].PPAR Research(IF 2.685), 2009, Vol.2009DOAJ
摘要:Thirty years after its discovery, the hepatitis B virus (HBV) still remains a major global public health problem. Worldwide, two billion subjects have been infected, 350 million have a chronic infection and more than 600 000 die annually of HBV-related liver disease or hepat...
作者:Philippe Mathurin , Samuel B. Ho ...
来源:[J].Digestive Diseases and Sciences(IF 2.26), 2019, Vol.64 (7), pp.1878-1892Springer
摘要:Abstract(#br) Background(#br)Alcohol-related liver disease is one of the most prevalent chronic liver diseases worldwide. Mechanisms involved in the pathogenesis of alcohol-related liver disease are not well understood. Oxylipins play a crucial role in numerous biological pr...
作者:Philippe Mathurin , François-René Pruvot ...
来源:[J].CardioVascular and Interventional Radiology(IF 2.138), 2015, Vol.38 (3), pp.685-692Springer
摘要:Abstract(#br) Purpose(#br) Most transplant centers use chemoembolisation as locoregional bridge therapy for hepatocellular carcinoma (HCC) before liver transplantation (LT). Chemoembolisation using beads loaded with doxorubicin (DEBDOX) is a promising technique that enables ...
作者:Philippe Mathurin , Mark Thursz
来源:[J].Journal of Hepatology(IF 9.858), 2019, Vol.70 (2), pp.314-318Elsevier
摘要:Summary(#br)In some areas of medicine the clinical development pathway through phase II and III clinical trials has been well mapped out and refined through extensive experience. In contrast, a number of key questions remain unanswered in the development of novel therapeutics for...
作者:Philippe Mathurin , Philippe Otal ...
来源:[J].Gastroenterology(IF 12.821), 2017, Vol.152 (1), pp.157-163Elsevier
摘要:Background & Aims(#br)There is controversy over the ability of transjugular intrahepatic portosystemic shunts (TIPS) to increase survival times of patients with cirrhosis and refractory ascites. The high rate of shunt dysfunction with the use of uncovered stents counteracts ...
作者:... Stanislas Pol , Alain Duhamel , Philippe Mathurin
来源:[J].Journal of Hepatology(IF 9.858), 2019, Vol.70 (5), pp.831-838Elsevier
摘要:Background & Aims(#br)Before antiviral therapy, kidney transplant recipients infected with hepatitis B virus (HBV) or hepatitis C virus (HCV) had poor outcomes. Since the 90s, nucleos(t)ide analogues have been widely used in HBV-infected patients, while interferon-based therapy w...

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