全部文献期刊会议图书|学者科研项目
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作者:... Claudio Toma , Holly Peay , Philip B. Mitchell
来源:[J].Journal of Affective Disorders(IF 3.295), 2020, Vol.265, pp.342-350
摘要:Abstract(#br)Background(#br)Polygenic risk scores (PRSs) summarise genetic risk in complex genetic disorders such as bipolar disorder (BD). The aim of this study was to gain in-depth, nuanced information regarding the understanding and experience of receiving a PRS for BD fr...
作者:... Melvin G. McInnis , Philip B. Mitchell , John I. Nurnberger
来源:[J].Journal of the American Academy of Child & Adolescent Psychiatry(IF 6.97), 2017, Vol.56 (12), pp.1073-1080
摘要:Objective(#br)Bipolar disorder (BD) is one of the most heritable psychiatric conditions and is associated with high suicide risk. To explore the reasons for this link, this study examined the interaction between traumatic stress and BD polygenic risk score in relation to suicidal...
作者:Philip B. Mitchell , Janice M. Fullerton ...
来源:[J].Psychiatry Research(IF 2.456), 2019, Vol.274, pp.49-57
摘要:Abstract(#br)Melatonin secretion and polysomnography (PSG) were compared among a group of healthy adolescents who were at high familial risk for bipolar disorder (HR) and a second group at low familial risk (LR). Adolescent participants (n = 12) were a mean age 14 ± 2.3 year...
作者:... Gloria Roberts , Philip B. Mitchell , Michael Breakspear
来源:[J].NeuroImage: Clinical, 2018, Vol.19, pp.71-81
摘要:Abstract(#br)Recent investigations have used diffusion-weighted imaging to reveal disturbances in the neurocircuitry that underlie cognitive-emotional control in bipolar disorder (BD) and in unaffected siblings or children at high genetic risk (HR). It has been difficult to quant...
作者:... Rhoshel Lenrootl , Philip B. Mitchell , Gloria Roberts
来源:[J].Journal of Affective Disorders(IF 3.295), 2019, Vol.245, pp.228-236
摘要:Abstract(#br)Background(#br)Increased white matter hyperintensities (WMHs) is one of the most consistent imaging findings amongst participants with bipolar disorder (BD). This study investigated WMHs in a young population at high genetic risk for bipolar disorder (HR).(#br)M...
作者:... Rohan Taylor , Philip B. Mitchell , Colleen K. Loo
来源:[J].The American Journal of Geriatric Psychiatry(IF 4.131), 2017
摘要:Objective(#br)To assess the efficacy and safety of subcutaneous ketamine for geriatric treatment-resistant depression. Secondary aims were to examine if repeated treatments were safe and more effective in inducing or prolonging remission than a single treatment.(#br)Methods(...
作者:Philip B. Mitchell , Janice M. Fullerton ...
来源:[J].Comprehensive Psychiatry(IF 2.376), 2017, Vol.78, pp.130-139
摘要:Abstract(#br)Background(#br)Adults with bipolar disorder (BD) have higher rates of substance use disorders (SUDs) compared to the general population. SUD rates in young offspring/relatives of BD probands, as well as factors which drive those rates, are not as well-characteri...
作者:Philip B. Mitchell , Peter R. Schofield
来源:[J].European Neuropsychopharmacology(IF 4.595), 2019, Vol.29, pp.S837-S838
摘要:Background(#br)Bipolar Disorder (BD) is a complex psychiatric condition with high heritability, the genetic architecture of which likely comprises both common variants of small effect and rare variants of higher penetrance. Multiplex families with high density of illness pro...
作者:Philip B. Mitchell , Peter Schofield
来源:[J].European Neuropsychopharmacology(IF 4.595), 2019, Vol.29, pp.S834-S835
摘要:Background(#br)Bipolar Disorder (BD) is a common, complex psychiatric condition characterized by recurrent fluctuations of mood. Historically, linkage approaches implicated a number of genetic loci, but signals typically failed to be replicated due to heterogeneity of family samp...
作者:... Kerry A. Sherman , Kate Dunlop , Philip B. Mitchell
来源:[J].European Neuropsychopharmacology(IF 4.595), 2019, Vol.29, pp.S843-S843
摘要:Background(#br)Many individuals with a family history of depression are concerned about their risks of developing major depressive disorder and/or bipolar disorder and the risks to their offspring. They report a range of unmet educational and psychological support needs in r...

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