全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:... Balázs Győrffy , Peter Schirmacher , Albrecht Stenzinger
来源:[J].BMC Medical Genomics(IF 3.466), 2017, Vol.10 (1)Springer
摘要:Inhibition of the PD-L1/PD-1 immune checkpoint axis represents one of the most promising approaches of immunotherapy for various cancer types. However, immune checkpoint inhibition is successful only in subpopulations of patients emphasizing the need for powerful biomarkers that ...
作者:Peter Schirmacher , Frederik Marmé ...
来源:[J].BMC Cancer(IF 3.333), 2016, Vol.16 (1)Springer
摘要:Abstract(#br) Background(#br)In Germany, most breast cancer patients are treated in specialized breast cancer units (BCU), which are certified, and routinely monitored. Herein, we evaluate up-to-date oncological outcome of breast cancer (BC) molecular subtypes in routine clinical...
作者:Peter Schirmacher , Arne Warth
来源:[J].Diagnostic Pathology(IF 1.85), 2016, Vol.11 (1)Springer
摘要:Abstract(#br) Background(#br)Inhibition of the oncogenic fusion-gene EML4-ALK is a current first-line approach for patients with stage IV non-small cell lung cancer. While FISH was established as the gold standard for identifying these patients, there is accumulating evidence tha...
作者:... Andreas Buness , Peter Schirmacher , Ruprecht Kuner
来源:[J].BMC Cancer(IF 3.333), 2011, Vol.11 (1)Springer
摘要:Abstract(#br) Background(#br)Aquaporins (AQPs) have been recognized to promote tumor progression, invasion, and metastasis and are therefore recognized as promising targets for novel anti-cancer therapies. Potentially relevant AQPs in distinct cancer entities can be determined by...
作者:Peter Schirmacher , Peter Sauer
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.7 (1)DOAJ
摘要:BACKGROUND AND AIMS: Bile analysis has the potential to serve as a surrogate marker for inflammatory and neoplastic disorders of the biliary epithelium and may provide insight into biliary pathophysiology and possible diagnostic markers. We aimed to identify biliary protein marke...
作者:... Hellmut G Augustin , Peter Schirmacher , Sergij Goerdt
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.7 (4)DOAJ
摘要:Liver sinusoidal endothelium is strategically positioned to control access of fluids, macromolecules and cells to the liver parenchyma and to serve clearance functions upstream of the hepatocytes. While clearance of macromolecular debris from the peripheral blood is performe...
作者:Peter Schirmacher , Dirk Jaeger
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.6 (12)DOAJ
摘要:The upcoming quantification and automation in biomarker based histological tumor evaluation will require computational methods capable of automatically identifying tumor areas and differentiating them from the stroma. As no single generally applicable tumor biomarker is available...
作者:... Jörg Kleeff , Helmut Friess , Peter Schirmacher
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.3 (7)DOAJ
摘要:BACKGROUND: Autoimmune pancreatocholangitis (AIPC) is an emerging, not completely characterized disease. Aim of this study was the comprehensive evaluation of a series of AIPC patients, who were diagnosed and treated in a European institution between January 2003 and July 2006. M...
作者:Peter Schirmacher , Arne Warth
来源:[J].Pathology(IF 2.657), 2018Elsevier
摘要:Summary(#br)The aim of this study was to subcategorise large cell carcinoma (LCC) with null immunophenotype according to the World Health Organization (WHO) Classification of 2015 into the existing groups of adenocarcinoma and squamous cell carcinoma by further molecular gen...

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