全部文献期刊会议图书|学者科研项目
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作者:Peng-Cheng Cai , Fan Yu ...
来源:[J].Respiratory Research(IF 3.642), 2017, Vol.18 (1)
摘要:Mucus overproduction is an important feature of asthma. Interleukin (IL)-4 is required for allergen-induced airway inflammation and mucus production. MUC5AC gene expression is regulated by transcript factors NF-κB. The intracellular Ca2+ ([Ca2+]i...
作者:Peng-Cheng Cai , Jian-Chu Zhang ...
来源:[J].Molecular Therapy(IF 7.041), 2017, Vol.25 (3), pp.728-738
摘要:Idiopathic pulmonary fibrosis (IPF) is a chronic progressive lung disease that typically leads to respiratory failure and death within 3–5 years of diagnosis. Sub-pleural pulmonary fibrosis is a pathological hallmark of IPF. Bleomycin treatment of mice is a an established pu...
作者:Peng-Cheng Cai , Fei Xiang ...
来源:[J].Toxicology and Applied Pharmacology(IF 3.975), 2015, Vol.283 (2), pp.75-82
摘要:Abstract(#br)Idiopathic pulmonary fibrosis (IPF) is a chronic progressive lung disease characterized by the development of subpleural foci of myofibroblasts that contribute to the exuberant fibrosis. Recent studies revealed that pleural mesothelial cells (PMCs) undergo epith...
作者:... Ju-Hong Yang , Chang-Kai Guo , Peng-cheng Cai
来源:[J].Cancer Letters(IF 4.258), 2007, Vol.253 (1), pp.108-114
摘要:Abstract(#br)We detected a strong upregulation of the mutated transketolase transcript (TKTL1) in human hepatoma cell line HepG2, whereas transketolase (TKT) and transketolase-like-2 (TKTL2) transcripts were not upregulated. We inhibited the expression of TKTL1 by RNAi in HepG2 c...
作者:Peng-Cheng Cai , Lin-Jie Song ...
来源:[J].BBA - Molecular Basis of Disease(IF 4.91), 2015, Vol.1852 (9), pp.1796-1804
摘要:Abstract(#br)Idiopathic pulmonary fibrosis (IPF) is a chronic progressive lung disease of unknown cause that typically leads to respiratory failure and death within 3–5 years of diagnosis. TGF-β1 is considered a major profibrotic factor. However, TGF-β1 is necessary but not ...
作者:Peng-Cheng Cai , Zhi-Hua Xiao
来源:[J].Bioscience Reports(IF 1.876), 2018, Vol.38 (6)
摘要:Objective: To explore whether aspirin (ASA) enhances the sensitivity of hepatocellular carcinoma (HCC) side population (SP) cells to doxorubicin (Doxo) via miR-491/ATP-binding cassette sub-family G member 2 (ABCG2). Methods: Non-SP and SP cells were isolated from MHCC-97L cell li...
作者:Peng-Cheng Cai , Jian-Feng Zheng
来源:[J].Anti-Cancer Drugs(IF 2.232), 2007, Vol.18 (4), pp.427-433
摘要:A plasmid carrying DNA to be transcribed into a small interfering RNA against transketolase-like-1 mRNA was constructed and transfected into a human colon cancer cell line. The mRNA expression of transketolase gene family in the human colon cell line was determined by real-time p...
作者:Peng-Cheng Cai , Feng Chen ...
来源:[J].Radiation Research(IF 2.698), 2013, Vol.179 (4), pp.485-492
摘要:Radiation leads to a rapid burst of reactive oxygen species (ROS), which is considered to be one of the major causes of radiation-induced injury. ROS have previously been shown to induce changes in cytosolic Ca2+ ([Ca2+]i)...
作者:Peng-cheng Cai , Xian-zhi Xiong
来源:[J].Journal of Huazhong University of Science and Technology [Medical Sciences](IF 0.581), 2013, Vol.33 (1), pp.22-26
摘要:Summary(#br)FIZZ/RELM is a new gene family named “found in inflammatory zone” (FIZZ) or “resistin-like molecule” (RELM). FIZZ1/RELMα is specifically expressed in lung tissue and associated with pulmonary inflammation. Chronic cigarette smoking up-regulates FIZZ1/RE...

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