全部文献期刊会议图书|学者科研项目
中外文文献  中文文献  外文文献
作者:Pawel Surowiak , Jan Budczies
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.8 (12)
摘要:In the last decade, optimized treatment for non-small cell lung cancer had lead to improved prognosis, but the overall survival is still very short. To further understand the molecular basis of the disease we have to identify biomarkers related to survival. Here we present the de...
作者:Pawel Surowiak , Axel Priebsch
来源:[J].Biochemical and Biophysical Research Communications(IF 2.406), 2006, Vol.348 (1), pp.153-157
摘要:Abstract(#br)The adenosine triphosphate binding cassette (ABC)-transporter ABCC2 (MRP2/cMOAT) can mediate resistance against the commonly used anticancer drugs cisplatin and paclitaxel. To overcome the ABCC2-depending drug resistance, two specific anti-ABCC2 small interfering RNA...
作者:... Maciej Zabel , Pawel Surowiak , Marcin Drag
来源:[J].Bioorganic & Medicinal Chemistry Letters(IF 2.338), 2009, Vol.19 (16), pp.4814-4817
摘要:Abstract(#br)Betulin and betulinic acid are naturally occurring pentacyclic triterpenes showing cytotoxicity towards a number of cancer cell lines. Unfortunately they are practically insoluble in aqueous media and therefore their overall absorption index is not satisfactory. We h...
作者:Pawel Surowiak , Zsolt Tulassay
来源:[J].Journal of Genetics(IF 0.876), 2007, Vol.86 (2), pp.103-109
摘要:Abstract(#br)There is a growing evidence, that antisense transcription might have a key role in a range of human diseases. Although predefined sense-antisense pairs were extensively studied, the antisense expression of the known sense genes is rarely investigated. We retriev...
作者:Pawel Surowiak , Maciej Kaczorowski ...
来源:[J].Oncology Letters(IF 0.237), 2016, Vol.12 (3), pp.1667-1674
摘要:Polo-like kinase 1 (PLK1) is a serine-threonine kinase that plays a crucialrole in the regulation of cell division. In addition, it acts as a modulator ofthe DNA damage response and as a novel factor in the maintenance of genome stabilityduring DNA replication. The present s...
作者:Zsofia Penzvalto , Pawel Surowiak , Balazs Gyorffy
来源:[J].Current Cancer Drug Targets(IF 4), 2014, Vol.14 (3), pp.259-273
摘要:Epithelial ovarian cancer (EOC) is the most deadly tumor of the female reproductive system. Despiteimprovements in understanding the biology of EOC, therapeutic strategies still depend on surgery and combination oftaxane and platinum agents. Here, we provide a summary of clinical...
作者:Zsofia Penzvalto , Pawel Surowiak , Balazs Gyorffy
来源:[J].Current Cancer Drug Targets(IF 4), 2014, Vol.14 (3), pp.259-273
摘要:Epithelial ovarian cancer (EOC) is the most deadly tumor of the female reproductive system. Despiteimprovements in understanding the biology of EOC, therapeutic strategies still depend on surgery and combination oftaxane and platinum agents. Here, we provide a summary of clinical...
作者:... Manfred Dietel , Hermann Lage , Pawel Surowiak
来源:[J].Oncology Reports(IF 2.297), 2009, Vol.22 (6), pp.1315-1323
摘要:One of the leading causes of chemotherapy failure in non-Hodgkin's lymphomas(NHLs) is multidrug resistance (MDR). MDR can be associated with expression ofmembers of the family of ABC-transporters. Since a correlation between expressionof cyclooxygenase-2 (COX-2) and MDR in variou...
作者:... Hermann Lage , Pawel Surowiak , Rafal Matkowski
来源:[J].Oncology Reports(IF 2.297), 2014, Vol.31 (4), pp.1777-1787
摘要:PARP-1 plays an important role in DNA damage repair and maintaining genomeintegrity by repairing DNA single-strand breaks (SSBs) by base excision repair(BER). The aim of the present study was to examine the expression of PARP-1 inbreast cancer (BC) patients and to assess the rela...

我们正在为您处理中,这可能需要一些时间,请稍等。

资源合作:cnki.scholar@cnki.net, +86-10-82896619   意见反馈:scholar@cnki.net

×