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作者:Pavlina Chelenkova , Rumena Petkova ...
来源:[J].Biotechnology & Biotechnological Equipment(IF 0.622), 2018, Vol.32 (6), pp.1558-1566
摘要:Abstract(#br)Efficient maintenance of the integrity of the endothelium of cerebral blood vessels is crucially important, especially when the vessel walls are subjected to greater-than-normal levels of stress. Persistently high levels of genotoxic stress may result from lower...
作者:Pavlina Chelenkova , Dimo Dimov ...
来源:[J].Biotechnology & Biotechnological Equipment(IF 0.622), 2015, Vol.29 (2), pp.351-356
摘要:Matrix metalloproteinases (MMPs) are a family of highly homologous extracellular Zn2+-dependent endopeptidases, also known as matrixins. MMP-2 (gelatinase A) and MMP-9 (gelatinase B) are considered to play a key role in a variety of physiological processes as well...
作者:Pavlina Chelenkova , Ivaylo Tournev
来源:[J].Biotechnology & Biotechnological Equipment(IF 0.622), 2016, Vol.30 (4), pp.623-643
摘要:ABSTRACT(#br)Neurons in the adult central nervous system (CNS) are subjected to high levels of oxidative damage that is usually promptly repaired. Transcribed genomic regions are repaired with priority over untranscribed regions. The prioritization of DNA repair in neurons result...
作者:Pavlina Chelenkova , Rumena Petkova ...
来源:[J].Biotechnology & Biotechnological Equipment(IF 0.622), 2011, Vol.25 (4), pp.2639-2641
摘要:ABSTRACT(#br)Brown trout (Salmo trutta fario) is a popular object of recreational fishing in Bulgaria and throughout Europe. Free-living (‘wild’) populations of brown trout are seen in many cold water rivers, and restocking of artificial as well natural water basins is carri...
作者:Pavlina Chelenkova , Rumena Petkova ...
来源:[J].Biotechnology & Biotechnological Equipment(IF 0.622), 2012, Vol.26 (2), pp.2894-2898
摘要:ABSTRACT(#br)Human impact on genetic variability of species is a prominent cause for loss of biodiversity on a global scale. The present work offers evidence that the genetic diversity in Bulgarian native populations of brown trout is already failing because of alteration of the ...
作者:Pavlina Chelenkova , Husein Yemendzhiev ...
来源:[J].Biotechnology & Biotechnological Equipment(IF 0.622), 2013, Vol.27 (6), pp.4217-4221
摘要:ABSTRACT(#br)HPV infection is a major pathogenetic factor in cervical carcinoma as well as in many of the squamous cancers of head and neck and other epithelial cancers. Persistence of HPV DNA detectable by routine methods is considered to be a risk factor for advanced CIN and, i...
作者:Pavlina Chelenkova , Elena Georgieva
来源:[J].Biotechnology & Biotechnological Equipment(IF 0.622), 2013, Vol.27 (6), pp.4208-4216
摘要:ABSTRACT(#br)The capacity for repair of damage in DNA may vary between clinically healthy people and in patients with different diseases and conditions, contributing to the risk for development of late-onset multifactorial disease, eligibility for different therapies and various ...
作者:Pavlina Chelenkova , Rumena Petkova
来源:[J].Biotechnology & Biotechnological Equipment(IF 0.622), 2012, Vol.26 (4), pp.3142-3147
摘要:ABSTRACT(#br)The DNA repair machinery of healthy human cells usually manages the consequences of the daily barrage of DNA damage for years and decades before any adverse effects related to genotoxic impact become manifest. There is significant variance, however, even between heal...
作者:Pavlina Chelenkova , Elena Georgieva
来源:[J].Biotechnology & Biotechnological Equipment(IF 0.622), 2014, Vol.28 (1), pp.2-7
摘要:ABSTRACT(#br)The individual variance in the efficiency of repair of damage induced by genotoxic therapies may be an important factor in the assessment of eligibility for different anticancer treatments, the outcomes of various treatments and the therapy-associated complications, ...

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