全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Paula Fernández-Calotti , Romina Gamberale ...
来源:[J].International Immunopharmacology(IF 2.417), 2005, Vol.6 (5), pp.715-723Elsevier
摘要:Abstract(#br)Fludarabine is a nucleoside analogue that has been successfully employed for the treatment of low-grade lymphoid malignancies and, more recently, in nonmyeloablative preparative regimens for stem cell transplantation, due to its strong cytotoxic activity on lymp...
作者:Paula Fernández-Calotti , Lars Jordheim ...
来源:[J].Biochemical Pharmacology(IF 4.576), 2003, Vol.66 (11), pp.2185-2191Elsevier
摘要:Abstract(#br)Administration of the adenosine analogue fludarabine (FLU) in vivo induces a profound and prolonged T lymphopenia which mainly affects CD4 + cells. To better understand the mechanistic basis underlying this preferential depletion, we analyzed the in vitro suscep...
作者:Paula Fernández-Calotti , Julieta Sanjurjo ...
来源:[J].Leukemia Research(IF 2.764), 2005, Vol.29 (11), pp.1277-1284Elsevier
摘要:Abstract(#br)Two main isoforms of Fcγ receptor II (CD32) have been described in humans: activatory FcγRIIA and inhibitory FcγRIIB. We have previously reported that B cells from a subset of chronic lymphocytic leukemia (B-CLL) patients express not only FcγRIIB, as normal B ly...

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