全部文献期刊会议图书|学者科研项目
中外文文献  中文文献  外文文献
作者:Patrick Lebok , Franziska Büscheck ...
来源:[J].Clinical Oral Investigations(IF 2.2), 2017, Vol.21 (5), pp.1503-1508
摘要:CD151 is a plasma membrane protein belonging to the tetraspanin family. CD151 represents a putative therapeutic target and has been suggested as a prognostic marker in several cancer types. The present study aims to investigate the prognostic relevance of immunohistochemical CD15...
作者:Patrick Lebok , David Dum ...
来源:[J].Molecular Medicine(IF 4.469), 2020, Vol.26 (1), pp.1252-1259
摘要:Abstract(#br)Background(#br)TFAP2D is a transcription factor important for modulating gene expression in embryogenesis. Its expression and prognostic role in prostate cancer has not been evaluated. Methods(#br)Therefore, a tissue microarray containing 17,747 prostate cancer ...
作者:Patrick Lebok , David Dum ...
来源:[J].Neoplasia, 2019, Vol.21 (9), pp.872-881
摘要:Abstract(#br)Dysregulation of S100A8 is described in many different human tumor types, but its role in prostate cancer is unknown. To evaluate the clinical relevance of S100A8 expression in prostate cancer, a tissue microarray containing 13,665 tumors was analyzed by immunohistoc...
作者:Patrick Lebok , Jakob R. Izbicki ...
来源:[J].Experimental and Molecular Pathology(IF 2.128), 2015, Vol.98 (3), pp.419-426
摘要:Abstract(#br)Histone deacetylases (HDACs) play an important role in tumor development and progression by modifying histone and non-histone proteins. In the current study we analyzed prevalence and prognostic impact of HDAC1 in prostate cancer. HDAC1 expression was analyzed by imm...
作者:Patrick Lebok , Christoph Fraune ...
来源:[J].Clinical Epigenetics, 2019, Vol.11 (1), pp.394-424
摘要:Abstract(#br)Background(#br)The clinical course of prostate cancer (PCa) is highly variable, demanding an individualized approach to therapy. Overtreatment of indolent PCa cases, which likely do not progress to aggressive stages, may be associated with severe side effects an...
作者:Patrick Lebok , Maximillian Lennartz ...
来源:[J].Acta Oncologica(IF 2.867), 2020, Vol.59 (3), pp.268-273
摘要:Abstract(#br)Background:(#br) Remodelling and spacing factor 1 (RSF1) is involved in the regulation of chromatin remodelling and represents a potential therapeutic target. High RSF1 expression has been linked to adverse tumour features in many cancer types, but its role in p...
作者:... Thorsten Schlomm , Waldemar Wilczak , Patrick Lebok
来源:[J].Tumor Biology(IF 2.518), 2016, Vol.37 (9), pp.12655-12663
摘要:Abstract(#br)Altered expression of the p16 tumor suppressor is frequently found in prostate cancer, but its role for tumor development and patient prognosis is disputed. In order to clarify the prognostic role of p16 and to draw conclusions on interactions with key molecular...
作者:Patrick Lebok , Sarah Minner ...
来源:[J].Pathology - Research and Practice(IF 1.213), 2014, Vol.210 (10), pp.649-655
摘要:Abstract(#br)Activated leukocyte cell adhesion molecule (ALCAM/CD166) is expressed in a number of malignancies ( e.g. prostate, breast, squamous cell carcinoma of the esophagus, lung and head and neck tumors). Based on studies in which ALCAM showed prognostic relevance in several...
作者:Patrick Lebok , Maria-Christina Tsourlakis ...
来源:[J].Oral Oncology(IF 2.695), 2012, Vol.48 (10), pp.991-996
摘要:Abstract(#br)Aims(#br)Epidermal growth factor (EGFR) is involved in angiogenesis, cell differentiation, proliferation and progression of many cancers and is an important therapy target in lung and colorectal cancer. To determine the potential applicability of EGFR targeted therap...
作者:Patrick Lebok , Andrea Hinsch ...
来源:[J].Oncology Letters(IF 0.237), 2018, Vol.16 (5), pp.6238-6244
摘要:Approximately 50% of prostate cancer types harbor the transmembrane protease,serine 2: Erythroblast transformation‑specific‑related gene (ERG) fusion, resultingin oncogenic expression of the ERG transcription factor. ERG represents an attractivetarget for potential future an...

我们正在为您处理中,这可能需要一些时间,请稍等。

资源合作:cnki.scholar@cnki.net, +86-10-82896619   意见反馈:scholar@cnki.net

×