全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Paraskevi Alexandrou , Eougken Dana ...
来源:[J].Tumor Biology(IF 2.518), 2014, Vol.35 (7), pp.6455-6465Springer
摘要:Abstract(#br)Extracellular signal-regulated kinase (ERK) has been considered as a critical regulator of diverse cellular processes such as proliferation, survival and motility, being implicated in the malignant transformation in several tissue types. The present study aimed ...
作者:Paraskevi Alexandrou , Efstratios Patsouris
来源:[J].Pathology & Oncology Research(IF 1.555), 2014, Vol.20 (2), pp.277-284Springer
摘要:Abstract(#br)Ephrin receptors (Ephs) are frequently overexpressed in a wide variety of human malignant tumors, being associated with tumor growth, invasion, metastasis and angiogenesis. The present study aimed to evaluate the clinical significance of Eph-A1, -A2, -A4 and -A7...
作者:Paraskevi Alexandrou , Nikolaos Tsoukalas ...
来源:[J].Tumor Biology(IF 2.518), 2015, Vol.36 (1), pp.315-327Springer
摘要:Abstract(#br)Hu-antigen R (HuR) is considered to play a central role in tumor formation, growth, and metastasis by binding to messenger RNAs (mRNAs) encoding proteins such as cyclooxygenase-2 (COX-2) and inducing their expression via mRNA stabilization and/or altered transla...
作者:Paraskevi Alexandrou , Ioanna Delladetsima ...
来源:[J].Pathology & Oncology Research(IF 1.555), 2016, Vol.22 (1), pp.189-196Springer
摘要:Abstract(#br)Hu-antigen R (HuR) is considered to play a crucial role in tumor formation and growth by binding to mRNAs encoding proteins such as Cyclooxygenase-2 (COX-2) and inducing their expression via mRNA stabilization and/or altered translation. The present study aimed ...
作者:Paraskevi Alexandrou , Androniki Louvrou ...
来源:[J].Breast Cancer Research and Treatment(IF 4.469), 2003, Vol.77 (2), pp.145-155Springer
摘要:Abstract(#br)Crucial event in the metastasis of cancer cells is the secretion of matrix metalloproteinases (MMPs), which are responsible for the degradation of extracellular matrix (ECM). Among them, matrix metalloproteinase-2 (MMP-2) is a gelatinase, which degrades basement...
作者:Paraskevi Alexandrou , Ioanna Delladetsima ...
来源:[J].Tumor Biology(IF 2.518), 2014, Vol.35 (1), pp.61-71Springer
摘要:Abstract(#br)Histone deacetylases (HDACs) have been associated with human malignant tumor development and progression, and HDAC inhibitors are currently being explored as anticancer agents in clinical trials. The present study aimed to evaluate the clinical significance of HDAC-1...
作者:Paraskevi Alexandrou , Elpida Poulaki ...
来源:[J].Pathology & Oncology Research(IF 1.555), 2016, Vol.22 (2), pp.269-275Springer
摘要:Abstract(#br)Ephrin receptors (Ephs) are frequently overexpressed in a wide variety of human malignant tumors, being associated with tumor growth, invasion, angiogenesis and metastasis. The present study aimed to evaluate the clinical significance of EphB4 and EphB6 protein expre...
作者:Paraskevi Alexandrou , Jose Rodriguez ...
来源:[J].Tumor Biology(IF 2.518), 2016, Vol.37 (3), pp.3647-3656Springer
摘要:Abstract(#br)Cannabinoid receptors (CB1R and CB2R) constitute essential members of the endocannabinoid system (ECS) which participates in many different functions indispensable to homeostatic regulation in several tissues, exerting also antitumorigenic effects. The present s...
作者:Paraskevi Alexandrou , Efstratios Patsouris
来源:[J].Journal of Cancer Research and Clinical Oncology(IF 2.914), 2012, Vol.138 (8), pp.1369-1377Springer
摘要:Abstract(#br) Purpose(#br)Focal adhesion kinase (FAK) and Src are protein tyrosine kinases, localized in the focal adhesions, which, upon activation interacts each other, regulate several cellular signaling pathways implicated in malignant transformation and disease progress...
作者:Paraskevi Alexandrou , John Sfiniadakis ...
来源:[J].Pathology & Oncology Research(IF 1.555), 2012, Vol.18 (4), pp.875-883Springer
摘要:Abstract(#br)Peroxisome proliferator-activated receptor-γ (PPAR-γ) has currently been considered as molecular target for the treatment of human metabolic disorders. PPAR-γ has also been implicated in the pathogenesis and progression of several types of cancer, being associat...

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