全部文献期刊会议图书|学者科研项目
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作者:Paraskevi Alexandrou , Androniki Louvrou ...
来源:[J].Breast Cancer Research and Treatment(IF 4.469), 2003, Vol.77 (2), pp.145-155Springer
摘要:Abstract(#br)Crucial event in the metastasis of cancer cells is the secretion of matrix metalloproteinases (MMPs), which are responsible for the degradation of extracellular matrix (ECM). Among them, matrix metalloproteinase-2 (MMP-2) is a gelatinase, which degrades basement...
作者:Paraskevi Alexandrou , Efstratios Patsouris ...
来源:[J].Disease Markers(IF 2.14), 2013, Vol.35 (4)Hindawi
摘要:Background . The receptor-binding cancer antigen expressed on SiSo cells (RCAS1) is a human tumor-associated antigen that has been considered to play a crucial role in tumor progression by enabling cancer cells to evade immune surveillance. The present study aimed to evaluat...
作者:Paraskevi Alexandrou , Ioanna Delladetsima ...
来源:[J].Pathology & Oncology Research(IF 1.555), 2016, Vol.22 (1), pp.189-196Springer
摘要:Abstract(#br)Hu-antigen R (HuR) is considered to play a crucial role in tumor formation and growth by binding to mRNAs encoding proteins such as Cyclooxygenase-2 (COX-2) and inducing their expression via mRNA stabilization and/or altered translation. The present study aimed ...
作者:Paraskevi Alexandrou , Elpida Poulaki ...
来源:[J].Pathology & Oncology Research(IF 1.555), 2016, Vol.22 (2), pp.269-275Springer
摘要:Abstract(#br)Ephrin receptors (Ephs) are frequently overexpressed in a wide variety of human malignant tumors, being associated with tumor growth, invasion, angiogenesis and metastasis. The present study aimed to evaluate the clinical significance of EphB4 and EphB6 protein expre...
作者:Paraskevi Alexandrou , Jose Rodriguez ...
来源:[J].Tumor Biology(IF 2.518), 2016, Vol.37 (3), pp.3647-3656Springer
摘要:Abstract(#br)Cannabinoid receptors (CB1R and CB2R) constitute essential members of the endocannabinoid system (ECS) which participates in many different functions indispensable to homeostatic regulation in several tissues, exerting also antitumorigenic effects. The present s...
作者:Paraskevi Alexandrou , Nikolaos Tsoukalas ...
来源:[J].Tumor Biology(IF 2.518), 2015, Vol.36 (1), pp.315-327Springer
摘要:Abstract(#br)Hu-antigen R (HuR) is considered to play a central role in tumor formation, growth, and metastasis by binding to messenger RNAs (mRNAs) encoding proteins such as cyclooxygenase-2 (COX-2) and inducing their expression via mRNA stabilization and/or altered transla...
作者:Paraskevi Alexandrou , Ioanna Giannopoulou ...
来源:[J].Gynecologic Oncology(IF 3.929), 2006, Vol.104 (3), pp.557-563Elsevier
摘要:Abstract(#br)Objectives.(#br)Vascular endothelial growth factors A and B (VEGF-A and VEGF-B) play a major role in angiogenesis and activate VEGF receptor 1 (VEGFR-1). However, the clinicopathologic and clinical value of VEGF-B and VEGFR-1 in invasive breast carcinoma remains uncl...
作者:Paraskevi Alexandrou , Konstantinos Giaslakiotis ...
来源:[J].Virchows Archiv(IF 2.676), 2010, Vol.457 (4), pp.457-466Springer
摘要:Abstract(#br)Hepatic progenitor cells (HPC) appear in a variety of liver diseases. Their occurrence in chronic hepatitis C (CHC) remains unclear, and triggering factors have to be elucidated. The presence of HPC in CHC was examined in relation to histological and virological para...
作者:Paraskevi Alexandrou , Jerzy Klijanienko ...
来源:[J].Pathology & Oncology Research(IF 1.555), 2010, Vol.16 (4), pp.497-507Springer
摘要:Abstract(#br)Focal Adhesion Kinase (FAK) and Src have been reported to regulate tumor growth, invasion, metastasis and angiogenesis. The present study aimed to evaluate by immunohistochemistry the clinical significance of FAK and Src expression in 108 patients with benign an...
作者:Paraskevi Alexandrou , Efstratios Patsouris
来源:[J].Journal of Cancer Research and Clinical Oncology(IF 2.914), 2012, Vol.138 (8), pp.1369-1377Springer
摘要:Abstract(#br) Purpose(#br)Focal adhesion kinase (FAK) and Src are protein tyrosine kinases, localized in the focal adhesions, which, upon activation interacts each other, regulate several cellular signaling pathways implicated in malignant transformation and disease progress...

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